Sökning: "Henrik Blomqvist"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Henrik Blomqvist.

  1. 1. Monocyte chemoattractant protein-1 and CC-chemokine receptor-2 in two different conditions related to atherosclerosis

    Författare :Henrik Blomqvist; Linköpings universitet; []
    Nyckelord :atherosclerosis; hypercholesterolaemia; coronary artery disease; inflammation; MCP-1; CCR2; CRP; MEDICINE; MEDICIN;

    Sammanfattning : Atherosclerosis is the leading cause of death in the industrialized parts of the world. The pathological process is characterised by increased lipid influx to the arterial wall due to elevated circulating levels of low density lipoprotein (LDL). LDL is oxidatively modified by reactive oxygen species forming oxLDL. LÄS MER

  3. 2. Semi-automatic Ontology Construction based on Patterns

    Författare :Eva Blomqvist; Kurt Sandkuhl; Henrik Eriksson; Ralf-D Kutsche; Enrico Motta; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Computer science; Datavetenskap;

    Sammanfattning : This thesis aims to improve the ontology engineering process, by providing better semiautomatic support for constructing ontologies and introducing knowledge reuse through ontology patterns. The thesis introduces a typology of patterns, a general framework of pattern-based semi-automatic ontology construction called OntoCase, and provides a set of methods to solve some specific tasks within this framework. LÄS MER

  4. 3. Individually Tailored Toxicity-based Chemotherapy : Studies on Patients with Primary and Metastatic Breast Cancer

    Författare :Henrik Lindman; Jonas Bergh; Carl Blomqvist; Peter Nygren; Bo Nordenskjöld; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; breast cancer; tailored chemotherapy; toxicity-based dosing; high-dose therapy; MR imaging; G-CSF; epirubicin; docetaxel; cyclophosphamide; 5-fluorouracil; Onkologi; Oncology; Onkologi;

    Sammanfattning : Standard dosing of chemotherapy based on body surface area (BSA) results in large individual differences in toxicity due to a large inter-patient variability in pharmacokinetics (PK) and pharmacodynamics (PD). This results in under-dosing in certain patients with a potentially weaker antitumoral effect. LÄS MER

  5. 4. Content Ontology Design Patterns: Qualities, Methods, and Tools

    Författare :Karl Hammar; Henrik Eriksson; Vladimir Tarasov; Eva Blomqvist; Harald Sack; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ontology; Ontology Design Pattern; Quality Model; eXtreme Design; XDP; WebProtégé;

    Sammanfattning : Ontologies are formal knowledge models that describe concepts and relationships and enable data integration, information search, and reasoning. Ontology Design Patterns (ODPs) are reusable solutions intended to simplify ontology development and support the use of semantic technologies by ontology engineers. LÄS MER

  7. 5. Towards an Ontology Design Pattern Quality Model

    Författare :Karl Hammar; Kurt Sandkuhl; Henrik Eriksson; Vladimir Tarasov; Eva Blomqvist; Arianit Kurti; Jönköping University; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ontology; OWL; Ontology Design Pattern; Semantic Web; Quality Model;

    Sammanfattning : The use of semantic technologies and Semantic Web ontologies in particular have enabled many recent developments in information integration, search engines, and reasoning over formalised knowledge. Ontology Design Patterns have been proposed to be useful in simplifying the development of Semantic Web ontologies by codifying and reusing modelling best practices. LÄS MER