Sökning: "Henric Zazzi"

Hittade 2 avhandlingar innehållade orden Henric Zazzi.

  1. 1. Human insulin-like growth factor binding protein-4 and -6 : gene structure and transcription regulation

    Författare :Henric Zazzi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IGF binding proteins IGFBP ; DNA sequencing; chromosomal localization; gene expression; Sp I; NF-kappa-B; methylation;

    Sammanfattning : Insulin-like growth factors (IGF-I and IGF-II) are among the more abundant growth factors isolated from bone tissue and are synthesized by various bone cells including osteoblasts. The activity of IGFs is controlled by a family of binding proteins (IGFBPs) divided into subfamilies depending on their individual affinity for IGFs. LÄS MER

  3. 2. The art of transcriptome reconstruction : with applications in Picea abies (L.) H. Karst

    Författare :Karl Johan Westrin; Olof Emanuelsson; Henric Zazzi; Lukas Käll; Jens Sundström; Jarkko Salojärvi; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transcriptome reconstruction; transcriptome assembly; transcript isoform detection; Picea abies; acrocona; cone setting; differential expression; gene families; miRNA; quality assessment; transkriptomrekonstruktion; sammansättning av transkriptom; detektering av transkriptisoform; rödgran; kottegran; kottsättning; differentiellt uttryck; genfamiljer; kvalitetsutvärdering; miRNA; Biotechnology; Bioteknologi;

    Sammanfattning : Transcriptome reconstruction is an important component in the bioinformatical part of transcriptome studies. When a reference genome is missing, highly fragmented or incomplete, a de novo transcriptome assembly is the transcriptome reconstruction approach of choice, since in such situations, a simple alignment (or mapping) would not necessarily give all theinformation concerning splice junctions, isoforms or even the full extent of the gene. LÄS MER