Sökning: "Hematopoietic Stem Cell Transplantation"

Visar resultat 11 - 15 av 146 avhandlingar innehållade orden Hematopoietic Stem Cell Transplantation.

1. 11. Stem Cell Plasticity Controlling Neuronal Differentiation Prior to Cell Transplantation

   Författare :Laurent Roybon; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Differentiation; Stem cells; Immunology; serology; Immunologi; serologi; transplantation;

   Sammanfattning : Parkinson's disease (PD) is the second most common neurodegenerative disease and affects 2% of the population over 65 years of age. The disease is characterized by the progressive loss of dopaminergic neurons. Over time, symptoms increase and, in particular, lead to a dramatic slowness of movements. LÄS MER

3. 12. Regulation of Hematopoietic Stem and Progenitor Cells by Bone Marrow Niche Components

   Författare :Hong Qian; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cell; Hematologi; extracellular fluids; Haematology; bone marrow; Hematopoiesis; extracellulära vätskor;

   Sammanfattning : Throughout the lifespan of an individual, enormous numbers of mature blood cells are generated by hematopoietic stem cells (HSCs) in the bone marrow (BM). The HSC is a cell that can self-renew to maintain the HSC pool and differentiate into all types of mature blood cells. LÄS MER

4. 13. Regulation of Hematopoietic Stem Cells

   Författare :Emma Rörby; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; hematopoietic stem cells; hematopoietic stem cell expansion; cord blood; transforming growth factor beta; Smad signaling; pigment epithelium derived factor; CD9;

   Sammanfattning : This thesis is about the regulation of hematopoietic stem cells (HSCs) that represent rare cells residing in the bone marrow (BM) of adults. They are multipotent cells that have the capacity to differentiate to all mature cells of the blood system and have the capacity to self-renew, i.e. generate new HSCs. LÄS MER

5. 14. To be or not to be, unraveling molecular mechanisms for lineage decisions in developing blood cells

   Författare :Robert Månsson; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; common lymphoid precursor CLP ; early B-cell factor 1 EBF1 ; B-cell; Stemcell; hematopoiesis; extracellulära vätskor; Immunology; serology; transplantation; Immunologi; serologi;

   Sammanfattning : All hematopoietic cells originate from hematopoietic stem cells (HSC) residing in the BM. The process of differentiation, through which HSCs generate progenitors and subsequently mature blood cells has been extensively studied but many of the regulatory mechanisms involved remains elusive. LÄS MER

7. 15. Pathways that govern hematopoietic stem cell fate

   Författare :Matilda Billing; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :hematopoies; Hematopoietic stem cell; TGF beta; Smad signaling; GATA2; p57;

   Sammanfattning : Hematopoietic stem cells (HSCs) compose a rare population of undifferentiated cells, residing in the bone marrow of adult individuals, ensuring life-long maintenance and replenishment of the blood system. This fantastic achievement is possible owing to two special characteristics of the HSCs: their ability to make copies of themselves (self-renew), and their capacity to differentiate to all lineages of the blood system. LÄS MER