Sökning: "Held"

Visar resultat 1 - 5 av 815 avhandlingar innehållade ordet Held.

  1. 1. Studies on stable angina pectoris : risk indicators, prognosis and effects of verapamil or metoprolol treatment

    Författare :Claes Held; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :angina pectoris; haemostasis; fibrinolysis; inflammation; lipids; platelets; ultrasound; intima-media thickness; plaques; metoprolol; verapamil; prognosis; ;

    Sammanfattning : Hemostatic and fibrinolytic variables, inflammatory parameters, catecholamines and lipid parameters were studied at baseline, in a long-term prospective study of 809 patients with stable angina pectoris, and compared to results obtained in healthy control subjects (n=50). The prognostic implications of the various parameters at baseline were evaluated, as well as possible influences of drug treatment on these variables and their prognostic implications were studied. LÄS MER

  3. 2. Large Eddy Simulations of Separated Compressible Flows around Wing Sections

    Författare :Jörgen Held; Strömningsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; turbulence; subgrid-scale; shock-boundary layer interaction; wing section; transonic; subsonic; compressible; separated; Large eddy simulation; LES; PVM; Mechanical engineering; hydraulics; vacuum technology; vibration and acoustic engineering; Maskinteknik; hydraulik; vakuumteknik; vibrationer; akustik;

    Sammanfattning : This thesis concerns numerical calculations of compressible separated flows, with and without shocks, around wing sections using Large Eddy Simulations (LES). The considered geometries are the NACA 0012 wing section and the ONERA AT15A wing section. LÄS MER

  4. 3. Epidemiological studies of Helicobacter pylori and its relation to cancer and precancerous lesions in the upper gastrointestinal tract

    Författare :Maria Held; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Helicobacter pylori; atrophic gastritis; gastric cancer; esophagus cancer;

    Sammanfattning : Helicobacter pylori infection is strongly associated with gastric cancer risk. The carcinogenic process is supposed to occur step by step, from a normal gastric epithelium via gastritis, atrophy, intestinal metaplasia to dysplasia. LÄS MER

  5. 4. Modelling of drug-effect on time-varying biomarkers

    Författare :Felix Held; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cortisol; TNFα; hierarchical modelling; turnover model; pharmacokinetic pharmacodynamic modelling; cortisol TNFα hierarchical modelling turnover model pharmacokinetic pharmacodynamic modelling;

    Sammanfattning : Model-based quantification of drug effect is an efficient tool during pre-clinical and clinical phases of drug trials. Mathematical modelling can lead to improved understanding of the underlying biological mechanisms, help in finding shortcomings of experimental design and suggest improvements, or be an effective tool in simulation-based analyses. LÄS MER

  7. 5. Fuel-Efficient Look-Ahead Control for Heavy-Duty Vehicles with Varying Velocity Demands

    Författare :Manne Held; Jonas Mårtensson; Oscar Flärdh; Ardalan Vahidi; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; look-ahead control; optimal control; powertrain control; advanced driver assistance systems; Electrical Engineering; Elektro- och systemteknik;

    Sammanfattning : The fuel consumption of heavy-duty vehicles can be reduced by using information about the upcoming road section when controlling the vehicles. Most manufacturers of heavy-duty vehicles today offer such look-ahead controllers for highway driving, where the information consists of the road grade and the velocity only has small variations. LÄS MER