Sökning: "Heike Hellmold"

Hittade 1 avhandling innehållade orden Heike Hellmold.

1. 1. Toxicological and endocrinolgical aspects of cytochrome P450 in breast and lung

   Författare :Heike Hellmold; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :cytochrome P450; breast; lung; metabolism;

   Sammanfattning : Cytochrome P450 (CYP) enzymes have well characterized functions in disposition and pharmacokinetics of xenobiotics as well as in biosynthesis and/or metabolism of endogenous compounds, such as steroid hormones, bile acids, arachidonic acid and its derivatives. Cytochrome P450 mediated metabolic activation is known to be a prerequisite for the cytotoxic and mutagenic activity of many environmental toxins and procarcinogens. LÄS MER