Sökning: "Heat shock proteins Hsps"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Heat shock proteins Hsps.

  1. 1. Heat shock proteins as vaccine adjuvants

    Författare :Khaleda Rahman Qazi; Carmen Fernández; Qijun Chen; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heat shock protein; vaccine; adjuvant; BCG; Immunology; Immunologi;

    Sammanfattning : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. LÄS MER

  3. 2. Heat shock proteins in exercised human skeletal muscle

    Författare :Mattias Folkesson; Fawzi Kadi; Britta Wåhlin-Larsson; Robert Kruse; Barbara Wessner; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endurance training; Resistance training; Muscle Fibre Type; Electrical Pulse Stimulation; Muscle Hypertrophy;

    Sammanfattning : Exercise is considered as an important stressor accompanied by concerted molecular and cellular changes leading to adaptations at the level of skeletal muscle size and function. An important protein family produced by cells in response to stressful conditions is the heat shock proteins (HSPs). LÄS MER

  4. 3. Regulation of Hsp70 function by nucleotide-exchange factors

    Författare :Naveen Kumar Chandappa Gowda; Claes Andréasson; Gary Jones; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Heat shock proteins Hsps ; Hsp70; Molecular chaperones; Nucleotide-exchange factors NEFs ; Protein quality control PQC ; Proteostasis; Ubiquitin-proteasome system; Cell Biology; cellbiologi;

    Sammanfattning : Protein folding is the process in which polypeptides in their non-native states attain the unique folds of their native states. Adverse environmental conditions and genetic predisposition challenge the folding process and accelerate the production of proteotoxic misfolded proteins. LÄS MER

  5. 4. Meticulous control of the T3SS of Yersinia is essential for full virulence

    Författare :Ann-Catrin Björnfot; Hans Wolf-Watz; Kelly T. Hughes; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yersinia; type III secretion; YscU; substrate specificity switch; heat shock proteins; VagH; methyltransferase; virulence; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The type III secretion system (T3SS) of pathogenic Yersinia pseudotuberculosis is involved in virulence. The syringe-like secretion system spans both bacterial membranes and is responsible for the ability of Yersinia to transfer toxic proteins (Yop proteins) into the eukaryotic target cell. LÄS MER

  7. 5. The use of protein biomarkers in ecotoxicology : Studies of oxidative and genotoxic stress in the blue mussel (Mytilus edulis)

    Författare :Andreas Prevodnik; Michael Tedengren; Tomas Bollner; Kari Lehtonen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; Ecotoxicology; ekotoxikologi;

    Sammanfattning : Many environmental pollutants, heavy metals and polyaromatic hydrocarbons (PAHs) among them, are toxic by oxidative stress. Oxidative stress may be defined as a state in an organism when its inherent capacity to handle oxyradicals is surpassed, and it may result in peroxidation of lipids, and damage to proteins and DNA. LÄS MER