Sökning: "Hazard ratio"

Visar resultat 1 - 5 av 231 avhandlingar innehållade orden Hazard ratio.

  1. 1. Estimation of hazard ratios from observational data with applications related to stroke

    Författare :Guilherme Barros; Jenny Häggström; Marie Eriksson; Daniel Nevo; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; survival analysis; causal inference; hazard ratios; marginal hazard ratio; stroke; balancing; Statistics; statistik;

    Sammanfattning : The objective of this thesis is to examine some challenges that may emerge when conducting time-to-event studies based on observational data. Time-to-event (also called survival) is a setting that involves analyzing how different factors may influence the length of time until an individual experiences the event of interest. LÄS MER

  3. 2. Associations of type 2 diabetes mellitus with cancer and autoimmune diseases. A population-based epidemiological study in Sweden

    Författare :Xiangdong Liu; Allmänmedicin och klinisk epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes mellitus; cancer; autoimmune disease; cause of death; hazard ratio; standardized incidence ratio; survival; risk factor;

    Sammanfattning : This thesis aimed to search for epidemiological evidence supporting the associations of type 2 diabetes mellitus (T2DM) with cancer and autoimmune diseases (ADs) by analysing several Swedish national registries. T2DM shares risk factors with cancer, such as obesity, diet, stress, and physical inactivity. LÄS MER

  4. 3. Interleukin 6 trans-signalling : cardiovascular risk marker or therapeutical target?

    Författare :Louise Ziegler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Interleukin (IL) 6 signals in two pathways. In classical signalling, essential in antimicrobial defence and tissue regeneration, IL6 binds the membrane- bound IL6 receptor (IL6R) which associates with the signal transducing receptor gp130. LÄS MER

  5. 4. Essays on the Assumption of Proportional Hazards in Cox Regression

    Författare :Inger Persson; Kenneth Carling; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Informatics; computer and systems science; Proportional hazards; Cox regression; Proportionality assumption; Informatik; data- och systemvetenskap; Informatics; computer and systems science; Informatik; data- och systemvetenskap; statistik; Statistics;

    Sammanfattning : This thesis consists of four papers about the assumption of proportional hazards for the Cox model in survival analysis. The first paper compares the hazard ratio estimated from the Cox model to an exact calculation of the geometric average of the hazard ratio when the underlying assumption of proportional hazards is false, i.e. LÄS MER

  7. 5. Renal insufficiency, mortality and myocardial infarction

    Författare :Martin Holzmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Patients with dialysis-dependent renal insufficiency (RI) have a markedly increased risk of dying or developing cardiovascular disease. Among patients who have coronary heart disease (CHD), moderate or severe RI is associated with increased mortality. LÄS MER