Sökning: "Hasan Tükenmez"

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1. 1. Influence of wobble uridine modifications on eukaryotic translation

   Författare :Hasan Tükenmez; Anders Byström; Tracy Nissan; Sebastian Leidel; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Elongator is a conserved six subunit protein (Elp1p-Elp6p) complex that is required for the formation of ncm5 and mcm5 side chains at wobble uridines in transfer RNAs (tRNAs). Moreover, loss-of-function mutations in any gene encoding an Elongator subunit results in translational defects and a multitude of phenotypic effects. LÄS MER