Sökning: "Hardy-Weinberg equilibrium"

Hittade 1 avhandling innehållade orden Hardy-Weinberg equilibrium.

1. 1. The Genetics of Systemic Lupus Erythematosus : The Specificity of IRF5 to SLE

   Författare :MV Prasad Linga Reddy; Marta Alarcön Riquelme; Dan Holmberg; Uppsala universitet; []
   Nyckelord :Molecular genetics; Systemic lupus erythematosus; Interferon regulatory factor 5; Transmission-Disequilibrium Test; Family-based association test; Linkage Disequilibrium; Hardy-Weinberg equilibrium; Genetik;

   Sammanfattning : The breakdown of self-tolerance is the main driving force behind susceptibility to SLE. When this occurs, T and B cells are activated in an uncontrolled manner and produce autoantibodies against self fragmented DNA, RNA and sometimes other parts of the cell such as cardiolipin, phosphatidylserine, etc. LÄS MER