Sökning: "Hans Elmlund"

Hittade 2 avhandlingar innehållade orden Hans Elmlund.

  1. 1. Protein structure dynamics and interplay : by single-particle electron microscopy

    Författare :Hans Elmlund; Hans Hebert; José Maria Carazo; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biophysics; biochemistry; molecular; Biophysical chemistry; Biofysikalisk kemi;

    Sammanfattning : Single-particle cryo-electron microscopy (cryo-EM) is a method capable of obtaining information about the structural organization and dynamics of large macromolecular assemblies. In the late nineties, the method was suggested to have the potential of generating “atomic resolution” reconstructions of particles above a certain mass. LÄS MER

  3. 2. Towards unbiased 3D reconstruction : in single-particle cryo-electron microscopy

    Författare :Dominika Elmlund; Hans Hebert; Sarah Butcher; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioengineering; Bioteknik;

    Sammanfattning : Cryo-electron microscopy of freestanding molecules (single-particles) plays a pivotal role in the difficult and pressing challenge of determining the structures of large macromolecular complexes. Molecular volumes are generated by aligning large sets of randomly oriented two-dimensional (2D) projection images in three dimensions (3D) before reconstruction is performed using tomographic techniques. LÄS MER