Sökning: "Hakon Leffler"
Hittade 4 avhandlingar innehållade orden Hakon Leffler.
1. Studies on the Role of UDP-Glucose Dehydrogenase in Polysaccharide Biosynthesis
Sammanfattning : Polysaccharides are found in all forms of life and serve diverse purposes. They are enzymatically synthesised from activated monosaccharide precursors, nucleotide sugars. One such nucleotide sugar is UDP-glucuronic acid, which is formed from UDP-glucose by the UDP-glucose dehydrogenase (UGDH) enzyme. LÄS MER
2. A New Look into Protein C Inhibitor : Posttranslational Modifications and their Functions
Sammanfattning : The influences of posttranslational modifications on the functions of the versatile serpin protein C inhibitor (PCI) were studied. PCI is a serine protease inhibitor that is expressed in many tissues and secreted to various fluids in human, including blood plasma, seminal plasma, and urine. LÄS MER
3. Design and Synthesis of Galectin Inhibitors
Sammanfattning : Galectins, a lectin family, have shown binding affinities towards b-galactosides. Galectins have been proposed to be involved in a wide range of functions like for example, cell growth, adhesion, migration, chemo taxis and apoptosis. They have also been associated with various cancer types. LÄS MER
4. Perturbation of the epithelial barrier by enteric pathogens
Sammanfattning : Gastrointestinal infections in humans have been associated with a number of diseased condition, including stomach ulcers, gastroenteritis, Crohn's disease, and rheumatic arthritis. Such infections often cause altered intestinal permeability through perturbation of the tight junctions that hold epithelial cells together. LÄS MER