Sökning: "HaCaT"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet HaCaT.

  1. 1. Cobalt in the hard metal production industry : exposure via inhalation and skin and the inflammatory response in human keratinocytes

    Författare :Maria Klasson; Eva Särndahl; Håkan Westberg; Magnus Lindberg; Alexander Persson; Kristina Jakobsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cobalt; cobalt chloride; skin; HaCaT; in vitro; cell viability; pro-inflammatory cytokines; NLRP3 inflammasome;

    Sammanfattning : Cobalt is a strong sensitizer and can cause contact allergy upon both direct contact or from airborne exposure on the skin. In the skin, keratinocytes are the first cells to come in contact with the metal and will react and respond to the danger by triggering an alarm system resulting in an inflammatory response in the skin. LÄS MER

  2. 2. Epidermal keratinocytes studied by X-ray microanalysis, with special reference to contact dermatitis : In vivo and in vitro studies of functional changes in human cells

    Författare :Anders Grängsjö; Uppsala universitet; []
    Nyckelord :Medical sciences; X-ray microanalysis; elements; epidermis; keratinocytes; proliferation; cell membrane damage; Ki67; irritants; intracellular elemental content; keratinocyte culture; HaCaT; NHEK; RT-PCR; immunohistochemistry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; anatomi; Human Anatomy;

    Sammanfattning : By determining the intracellular elemental content, information can be obtained on the physiological status of cells. The cellular content of sodium, magnesium, phosphorus, sulfur, chloride, potassium and calcium can be indicative for proliferation, cell membrane damage or cell death. LÄS MER

  3. 3. Molecular and microscopical analysis of pathogenic streptococci - studies on surface proteins interacting with human cells and extracellular matrix

    Författare :Marta Bober; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pyogenes; streptococcal leucine rich repeat protein; M protein; collagen; keratinocytes;

    Sammanfattning : Association to specific host tissue structures allows pathogenic bacteria to establish an infection and facilitates the spread within its host. Interactions between bacterial surface structures and human proteins might determine the outcome of the infection. Streptococcus pyogenes (S. LÄS MER

  4. 4. Application of magnetic nanoparticles and reactive filter materials for wastewater treatment

    Författare :Ramnath Lakshmanan; Gunaratna Kuttuva Rajarao; Erik Dahlquist; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Reactive filter materials; magnetic nanoparticles; wastewater treatment process; nutrient reduction; sludge water content; toxicity of magnetic nanoparticles;

    Sammanfattning : Lately sewage wastewater treatment processes (WWTP) are facing challenges due to strict regulations in quality of effluent standards and waste production. The reuse of wastewater treatment effluents is rapidly gaining attention as a means of achieving sustainable water supply. Therefore, new methods are required to achieve an efficient WWTP. LÄS MER

  5. 5. Molecular Tools for Detection and Characterization of Proteins and Extracellular Vesicles in Health and Disease

    Författare :Ehsan Manouchehri Doulabi; Masood Kamali-Moghaddam; Lucia Mincheva-Nilsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High-resolution mass spectrometry; Proximity ligation assay; Proximity extension assay; Thymidine kinase 1; in situ PLA; High-throughput.; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Detecting molecules involved in cancer is critical for cancer research and diagnostics. To achieve this goal, sensitive protein detection is essential to improving the chances of finding, verifying, validating and developing valuable biomarkers. LÄS MER