Sökning: "HUMAN mitochondrial DNA"
Visar resultat 1 - 5 av 110 avhandlingar innehållade orden HUMAN mitochondrial DNA.
1. The consequences of DNA lesions for mitochondrial DNA maintenance
Sammanfattning : Eukaryotic cells have their own energy-producing organelles called mitochondria. The energy is stored in the adenosine triphosphate (ATP) molecule and is produced via the oxidative phosphorylation process inside the mitochondria. Thirteen of the essential proteins required for this process are encoded on the mitochondrial DNA (mtDNA). LÄS MER
2. Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells
Sammanfattning : Sepsis is a devastating disease that is caused by the host’s response to an overwhelming infectious process. As sepsis progresses, organs distant from the site of infection become affected and sepsis-induced multiple organ failure ensues. LÄS MER
3. Human adenovirus – host cell interplay : The role of the cellular zinc finger proteins and mitochondrial DNA
Sammanfattning : Human adenovirus (HAdV) is an abundant DNA virus with significant clinical relevance since it cauces a variety of respiratory, ocular, and gastrointestinal diseases. It is also intensively used as a therapeutic tool to treat cancers and to boost immune responses. LÄS MER
4. Regulation of Human Mitochondrial DNA Replication and Transcription
Sammanfattning : Mitochondria are organelles in eukaryotic cells, which through oxidative phosphorylation (OXPHOS) produce most of the ATP used to drive cellular processes. The organelle contains its own genetic material, mitochondrial DNA (mtDNA), which encodes 13 key components of the OXPHOS machinery. LÄS MER
5. Mitochondria and Human Evolution
Sammanfattning : Mitochondrial DNA (mtDNA) has been a potent tool in studies of the evolution of modern humans, human migrations and the dynamics of human populations over time. The popularity of this cytoplasmic genome has largely been due to its clonal inheritance (in Man) allowing the tracing of a direct genetic line. LÄS MER