Sökning: "HTLV-I"

Hittade 4 avhandlingar innehållade ordet HTLV-I.

  1. 1. Cyclic nucleotide signalling systems in vascular smooth muscle cells and immune system cells with special reference to phosphodiesterases PDE3 and PDE4

    Författare :Dag Ekholm; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HTLV-I; multiple sclerosis; proliferation; phosphorylation; T-lymphocytes; vascular smooth muscle; cloning; protein kinase A; cGMP; cAMP; PDE4; Phosphodiesterase; PDE3; cilostamide; rolipram; Histology; cytochemistry; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

    Sammanfattning : The cyclic nucleotide signalling systems are important in vascular smooth muscle and in the immune system, and are of interest from a pharmacological point of view. Drugs which interfere with the cyclic nucleotide levels have profound effects on heart, blood vessels and airways and have actual or potential use in several important diseases, such as heart failure, hypertension, arteriosclerosis, asthma and autoimmune diseases. LÄS MER

  3. 2. The causation of konzo : studies on a paralytic disease in Africa

    Författare :Thorkild Tylleskär; Uppsala universitet; []
    Nyckelord :Spastic paraparesis; konzo; cassava; cyanide; thiocyanate; inorganic sulphate; HTLV-I; MEDICINE; MEDICIN;

    Sammanfattning : Epidemics of a permanent, non-progressive spastic paraparesis with sudden onset hasbeen reported from several rural areas of sub-Saharan Africa. Studies in East Africasuggested an association with dietary cyanide intake from unprocessed cassava. LÄS MER

  4. 3. Prevention of transfusion transmitted infections : donor screening and characteristics of recipient populations

    Författare :Elsa Tynell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HTLV-I and II; blood donor screening; transfusion recipients; case-mix; survival rates; false-reactive test results; cost effectiveness;

    Sammanfattning : Minimising the risk for transfusion transmitted infections (TTIs) relies on selection of safe donors, including microbiological screening, and avoidance of unnecessary transfusions. Blood donor screening for HTLV-I and II, was introduced in Sweden in 1994. LÄS MER

  5. 4. On the Site of the Lesion in Konzo : Clinical and Neurophysiological Studies on a Non-Progressive Upper Motor Neuron Disorder

    Författare :Desire Tshala-Katumbay; Andrew Eisen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Konzo; upper motor neuron diseases; WHO criteria; electroencephalography; evoked potentials; brain involvement; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : Konzo is a permanent spastic para/tetraparesis occurring in undernourished populations in Africa relying on insufficiently processed bitter cassava, which contains cyanogenic compounds, as staple food. Its pathogenetic mechanism is unknown. Our studies aimed at clarifying the lesion in konzo. LÄS MER