Sökning: "HT-29"

Visar resultat 1 - 5 av 23 avhandlingar innehållade ordet HT-29.

  1. 1. Alkaline Sphingomyelinase; A Potential Inhibitor in Colorectal Carcinogenesis

    Författare :Erik Hertervig; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; cancer; Cytologi; cancerology; oncology; Cytology; Gastroenterologi; Gastro-enterology; HT-29; MIN mouse; FAP; colorectal cancer; human; alkaline sphingomyelinase;

    Sammanfattning : Sphingomyelin (SM) is present both in eucaryotic cells and the diet. Sphingomyelinase (SMase) hydrolyses SM and generates ceramide that has been implicated in the regulation of cell growth, differentiation and apoptosis. Previously a SMase with alkaline pH optimum was identified in the intestinal tract. LÄS MER

  3. 2. THE INFLUENCE OF LACTOBACILLI AND STAPHYLOCOCCUS AUREUS ON IMMUNE RESPONSIVENESS IN VITRO

    Författare :Yeneneh Haileselassie; Eva Sverremark-Ekström; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytokine; T cells; immune response; HT-29; Intestinal epithelial cells; Lactobacillus; Staphylococcus aureus; bacteria and infants; immunologi; Immunology;

    Sammanfattning : Alteration of gut microbiota has been associated with development of immune mediated diseases, such as allergy. In part, this could be due to the influence of microbes in shaping the immune response. LÄS MER

  4. 3. Magnetomotive ultrasound for nanomedicine : a mechanistic approach to detection, evaluation and safety assessment

    Författare :Sandra Sjöstrand; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetomotive; ultrasound; finite element analysis; cancer diagnosis; HT-29; Caco-2;

    Sammanfattning : Cancer is one of the leading causes of death worldwide, but reliable diagnosis and staging can contribute to optimal treatment planning, and is a crucial factor in reducing mortality and maintaining quality of life. Soft tissue mechanical properties are promising indicators of cancer that can be assessed non-invasively using functional imaging. LÄS MER

  5. 4. Protein kinase C-dependent regulation of the epithelial barrier

    Författare :Anita Sjö; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The intestinal epithelium is essential for the absorption of nutrients and for the defence against harmful substances in the gut. The permeability and barrier functions of epithelia are mainly controlled by the intercellular tight junctions. LÄS MER

  7. 5. Characterization of Escherichia coli colonizing the gastrointestinal tract and urinary tract catheters

    Författare :Xiaoda Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Commensal and pathogenic bacteria express biofilm behaviour which is thought to alter bacteria-host interactions and contribute to colonization and persistence. In the current thesis, the epidemiology of biofilm formation in gastrointestinal commensal Escherichia coli and E. coli isolated from urinary catheters is described. LÄS MER