Sökning: "HPLC ESI-MS"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden HPLC ESI-MS.

1. 1. Interfacing HPLC with MALDI- and ESI-MS for Automated High Sensitivity Analysis of Proteins and Peptides

   Författare :Tasso Miliotis; Lund Institutionen för kliniska vetenskaper; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; automated; phosphorylation; ZAP-70; peptides; proteins; comprehensive; multidimensional; two-dimensional; piezoelectric; microdispenser; flow-through; ESI-MS MS; Capillary HPLC; MALDI-TOF MS; Analytical chemistry; Analytisk kemi;

   Sammanfattning : The research described in this thesis has an interdisciplinary approach dealing with chemical, biological, and technical issues. One objective was to interface miniaturized liquid chromatography (LC) to mass spectrometry, i.e. MALDI-TOF MS and ESI-MS, in an unattended mode for high sensitivity determination of proteins and peptides. LÄS MER

3. 2. Methods for structural studies of an antibody, screening metabolites in rat urine and analysis of spent cell cultivation media using LC/ESI-MS and chemometrics

   Författare :Leila Zamani; Sven P. Jacobsson; Jonas Bergqvist; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Screening; Fingerprinting; metabolomics; Protein drugs; Mammalian Cell lines; LC ESI-MS; chemometrics; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

   Sammanfattning : This thesis describes bioanalytical methods for generating fingerprints of biological systems for extracting relevant information with (protein) drugs in focus. Similarities and differences between samples can reveal the hidden relevant information, which can be used to optimize the production and facilitate the quality control of such protein drugs during their development and manufacture. LÄS MER

4. 3. Resin acids in commercial products and the work environment of Swedish wood pellets production : Analytical methodology, occurrence and exposure

   Författare :Sara Axelsson; Ulrika Nilsson; Kåre Eriksson; Håkan Westberg; Martin Harper; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Rosin; resin acids; HPLC ESI-MS; air sampling; urine samples; wood pellets; wood dust; Analytical Chemistry; analytisk kemi;

   Sammanfattning : The aims of the work this thesis is based upon were to develop convenient analytical procedures for determining resin acids in biological and environmental matrices, and apply them to enhance understanding of the occurrence, exposure to and uptake by exposed individuals of resin acids. Particular focus has been on the workplace environment of the Swedish wood pellets industry. LÄS MER

5. 4. Essentially Lipids : Analytical methods for the characterization of lipid materials

   Författare :Petter Olsson; Bengt Herslöf; Jan Holmbäck; Torgny Fornstedt; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipids; Chromatography; HPLC; Charged Aerosol Detection; Evaporative light scattering detection; mass spectrometry; Analytical Chemistry; analytisk kemi;

   Sammanfattning : This thesis describes analytical methods for chromatographic characterizations of lipids in biological and technical systems.Lipids are a group of compounds with a central role in all known forms of life. In addition to the biological roles, lipids are also components in many products of our daily usage. LÄS MER

7. 5. Microwave heating effects on degradation and migration of additives from polypropylene packaging

   Författare :Jonas Alin; Minna Hakkarainen; Jiebing Li; Anna Finne Wistrand; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Polymer chemistry; Polymerkemi;

   Sammanfattning : The effect of different food types, polymer qualities and microwaves on the overall and specific migration during microwave heating of plastic packaging was investigated to better understand the packaging-food interactions and the effect of microwaves on food packaging. This work focuses on the migration of chemical compounds to food simulants from commercially available polypropylene packages. LÄS MER