Sökning: "HP1a"

Hittade 3 avhandlingar innehållade ordet HP1a.

1. 1. Aneuploidy compensatory mechanisms and genome-wide regulation of gene expression in Drosophila melanogaster

   Författare :Lina Lundberg; Jan Larsson; Brian Oliver; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genome-wide gene regulation; aneuploidy; buffering; HP1a; POF; SETDB1; Su var 3-9; MSL; roX; genetik; Genetics;

   Sammanfattning : Stimulation or repression of gene expression by genome-wide regulatory mechanisms is an important epigenetic regulatory function which can act to efficiently regulate larger regions or specific groups of genes, for example by compensating for loss or gain of chromosome copy numbers. In Drosophila melanogaster there are two known chromosome-wide regulatory systems; the MSL complex, which mediates dosage compensation of the single male X-chromosome and POF, which stimulates expression from the heterochromatic 4th chromosome. LÄS MER

3. 2. Epigenetics and targeting mechanisms in Drosophila melanogaster

   Författare :Margarida Figueiredo; Jan Larsson; Victoria Meller; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Aneuplodies; HP1a; POF; MSL; non-coding RNAs; genetik; Genetics;

   Sammanfattning : .... LÄS MER

4. 3. BEN-solo proteins in genome architecture and function

   Författare :Malin Ueberschär; Qi Dai; Mattias Mannervik; Nicola Iovino; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene regulation; transcription; insulators; genome architecture; Polymerase II pausing; chromatin; Drosophila development; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Eukaryotic genomes are organized in a complex manner inside the nucleus of each cell. Chromatin insulators are DNA elements that help to fold the linear DNA fiber in three-dimensional space and partition regulatory gene units. LÄS MER