Sökning: "HNE"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet HNE.

  1. 1. Oxidation of marine oils during in vitro gastrointestinal digestion and its effects on stress in human intestinal Caco-2 cells

    Författare :Cecilia Tullberg; Chalmers tekniska högskola; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; lipid oxidation; human digestive fluids; LC n-3 PUFAs; Caco-2 cells; marine oils; HNE; MDA; in vitro digestion; HHE; gastrointestinal; aldehydes;

    Sammanfattning : Marine oils are attracting public interest due to the preventive effects, e.g., on inflammation, which are linked to the long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs). However, LC n-3 PUFAs are highly susceptible to oxidation, which could interfere with their positive effects. LÄS MER

  3. 2. Oxidation of fish lipids during gastrointestinal in vitro digestion

    Författare :Karin Larsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TBARS; HHE; salmon; lipids; TIM; fish; HNE; in vitro digestion; gastrointestinal; aldehydes; cod liver oil; n-3 PUFA; herring; lipid oxidation; MDA;

    Sammanfattning : Fish and many other marine organisms, contain long chain n-3 polyunsaturated fatty acids (LC n-3 PUFA), e.g. eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). EPA and DHA has shown beneficial effects in diseases related to inflammatory processes, such as cardiovascular diseases. LÄS MER

  4. 3. Genetic variability commonly affecting neurodegeneration and neuroinflammation

    Författare :Mikael Ström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Loss of nerve cells and axons is a common feature of common complex neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases. However, also Multiple Sclerosis (MS), primarily an autoimmune disorder, has a prominent neurodegenerative component. LÄS MER

  5. 4. Characterization of α-synuclein oligomers : Implications for Lewy Body Disorders

    Författare :Thomas Näsström; Martin Ingelsson; Joakim Bergström; Lars Lannfelt; Poul Henning Jensen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; Alpha-synuclein; Lewy bodies; Oligomers; Reactive aldehydes; monoclonal antibody; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy are disorders featuring accumulation of Lewy bodies in brain. The main component of these large insoluble intracellular inclusions is the presynaptic protein alpha-synuclein (α-synuclein). LÄS MER

  7. 5. PTEN and Akt signalling in Alzheimer’s disease

    Författare :Annika Rickle; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PTEN; Akt; GSK3beta; post-mortem brain; rat primary cortical neurons;

    Sammanfattning : Akt / protein kinase B is an important cell survival kinase that modulates the activity of a range of pro-apoptotic proteins. A major downstream target of Akt is glycogen synthase kinase-3beta (GSK3beta) that phosphorylates the microtubule-associated protein tau. LÄS MER