Sökning: "HLA-A3"

Hittade 3 avhandlingar innehållade ordet HLA-A3.

  1. 1. Immunogenetic studies of multiple sclerosis

    Författare :Arturs Ligers; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Multiple sclerosis; CTLA-4; HLA-A2; HLA-A3; HLA-DRB1*15; HLA-DRB1*;

    Sammanfattning : Multiple sclerosis (MS) is an inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS). Several genetic factors are likely to be of importance for MS rather than one factor. LÄS MER

  2. 2. The transferrin polymorphism : population genetics and associations with reproductive hazards and disease

    Författare :Carin Sikström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Human serum transferrin (TF) carries iron from the intestine, reticuloendothelial system and liver parenchymal cells to proliferating cells in the body. TF is highly polymorphic, and previous findings of associations between TF types and reproductive hazards in different species suggest that the TF polymorphism may be involved in natural selection and susceptibility to disease. LÄS MER

  3. 3. Analysis of HLA-A2 frequency as prognostic and/or risk factors in ovarian cancer patients

    Författare :Zaynab Gamzatova; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Major histocompatibility complex antigens are mandatory for the immune response, and genetic imbalance may be linked to tumour escape. The HLA-A2 allele in Scandinavia has a high prevalence; it decreases with latitude and also with ovarian cancer mortality in Europe. LÄS MER