Sökning: "HLA Antigens"

Visar resultat 1 - 5 av 96 avhandlingar innehållade orden HLA Antigens.

  1. 1. Multiplex HLA-DR-DQ genotyping : for genetic epidemiology and clinical risk assessment

    Författare :Ewa Lavant; Malmö högskola; []
    Nyckelord :HLA-DRB1; HLA-DQB1; HLA-DQA1; PCR-SSP; type 1 diabetes; celiac disease; autoimmune disease; capillary gel electrophoresis; genotyping;

    Sammanfattning : The human leukocyte antigens (HLA) are highly polymorphic cell surface proteins encoded in the major histocompatibility complex (MHC) region on chromosome 6. The HLA system has been well known as transplantation antigens but the primary biological role of the HLA molecules is regulation of immune response by presenting peptide fragments to T-lymphocytes. LÄS MER

  3. 2. HLA-DR transplantation antigens : tissue distribution and structure

    Författare :Klas Wiman; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. Expression of Tissue Antigens in Human Pluripotent Stem Cells and Alterations During Differentiation : Potential application in regenerative medicine for treatment of terminal cell and organ failure

    Författare :Karin Säljö; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pluripotent stem cells; Differentiation; Histo-blood group antigens; HLA; Tissue antigens; Sialyl-lactotetra; Cell surface antigens; Transplantation; Regenerative medicine;

    Sammanfattning : The major limiting factor in the treatment of patients with end-stage organ failure is the insufficient number of human organs available for transplantation. An unlimited access to human cells, tissues and organs would also open up possibilities to treat several chronic diseases, such as diabetes, neurological and cardiovascular diseases, affecting millions of patients worldwide. LÄS MER

  5. 4. Studies on membrane integration and glycosylation of HLA-antigens

    Författare :Bengt Curman; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  7. 5. A Clinical and Genetic Study of Psoriatic Arthritis

    Författare :Gerd-Marie Alenius; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; Psoriatic arthritis; prevalence; inflammatory manifestations; genetic loci; HLA; TNFB; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; Clinical Genetics; klinisk genetik;

    Sammanfattning : Psoriatic arthritis (PsA) is an inflammatory joint disease associated with psoriasis. PsA has a heterogeneous pattern, expressed by different manifestations such as mild mono-oligoarthritis or very severe, erosive and destructive polyarthritis. Measurable inflammatory activity is not always prominent. LÄS MER