Sökning: "HIV-integrase inhibitors"

Hittade 1 avhandling innehållade orden HIV-integrase inhibitors.

  1. 1. Palladium-Catalysed Couplings in Organic Synthesis Exploring Catalyst-Presenting Strategies and Medicinal Chemistry Applications

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Alejandro Trejos; Mats Larhed; Jianliang Xiao; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mizoroki-Heck arylation; Suzuki coupling; domino reaction; stereoselective; palladium; chelation control; vinyl ether; HIV-protease inhibitors; HIV-integrase inhibitors; Kemi med inriktning mot organisk kemi; Chemistry with specialization in Organic Chemistry;

    Sammanfattning : Palladium-catalysed coupling reactions have been embraced by synthetic chemists as one of the preferred means for smooth formation of new carbon-carbon bonds: a truly ubiquitous methodology of synthesizing complex molecules.This thesis describes the study of a series of palladium(0)-catalysed C2-arylations of a 1-cyclopentenyl ether, equipped with a chiral (S)-N-methyl-pyrrolidine auxiliary. LÄS MER