Sökning: "HIPPOCAMPUS THESIS EXERCISE"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden HIPPOCAMPUS THESIS EXERCISE.

  1. 1. Brain Regeneration - in vitro and in vivo studies of exercise-related effects on brain plasticity

    Författare :Cecilia Bull; Göteborgs universitet; []
    Nyckelord :brain; neural progenitor cells; stem cells; hippocampus; corpus collosum; rat; mouse; regeneration; neurogenesis; oligodendrogenesis; irradiation; exercise;

    Sammanfattning : Neural stem and progenitor cells in the germinal regions of the adult brain, such as the hippocampus, are of great interest, because they provide the possibility for enhanced brain plasticity or can contribute to endogenous cell replacement after injury or disease. Voluntary exercise was recently shown to robustly induce cellular and structural plasticity, thereby contributing to overall brain health. LÄS MER

  3. 2. Differential effects of voluntary running on hippocampal plasticity in the adult rat brain

    Författare :Andrew Stuart Naylor; Göteborgs universitet; []
    Nyckelord :exercise; hippocampus; stress; progenitor proliferation; neurogenesis; trophic factors; frontal cortex; spatial memory; rat; pCREB; endogenous opioids;

    Sammanfattning : The continuation of neuronal birth from dividing neural stem cells in the dentate gyrus of the hippocampus throughout adulthood is known to play an important role in maintaining normal hippocampal function, such as memory and learning. Negative alterations in the levels of adult neurogenesis have also been linked to several neurodegenerative diseases, including Alzheimer s disease and mood disorders such as depression. LÄS MER

  4. 3. Physical exercise as a preventive strategy for disorders affecting the brain. The effect on neuroinflammation

    Författare :Martina Svensson; Neuroinflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical activity; Exercise; Neuroinflammation; Microglia; Cytokines; Behavior; Dementia; Depression; Brain ischemia; Alzheimer’s disease; Vascular dementia; Parkinson’s disease;

    Sammanfattning : Physical activity is associated with lower risks of developing dementia, Parkinson’s disease (PD) and depression. Furthermore, being physically active prior to brain ischemia appears to help the recovery process. LÄS MER

  5. 4. Neurogenesis and gliogenesis after focal brain ischemia. Modulation by enriched environment and exercise

    Författare :Mila Komitova; Göteborgs universitet; []
    Nyckelord :astrocyte; hippocampus; neural progenitor cells; neural stem cells; neurogenesis; neurotrophins; rat; regeneration; rehabilitation; stroke;

    Sammanfattning : New neurons are formed from dividing neural stem cells in restricted areas in the adult mammalian brain: the dentate gyrus of the hippocampal formation (DG) and the forebrain subventricular zone (SVZ). New glia also form constitutively and seem to be important for neuronal function. LÄS MER

  7. 5. Brain function and glucocorticoids in obesity and type 2 diabetes including effects of lifestyle interventions

    Författare :Andreas Stomby; Tommy Olsson; Mats Ryberg; Carl-Johan Boraxbekk; Alasdair MacLullich; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; type 2 diabetes; glucocorticoid; cortisol; 11beta hydroxysteroid dehydrogenase type 1; episodic memory; functional magnetic resonance imaging; paleolithic diet; exercise; Internal Medicine; invärtesmedicin; medicin; Medicine;

    Sammanfattning : Background Obesity and associated metabolic dysregulation are linked to impaired cognitive function and alterations in brain structure, which increases the risk of age-related dementia. Increased glucocorticoid (GC) exposure may be a potential mediator of these negative effects on the brain. LÄS MER