Sökning: "HER3"

Visar resultat 11 - 15 av 15 avhandlingar innehållade ordet HER3.

  1. 11. Human Epidermal Growth Factor Receptors and Biological Effects of HER-directed Molecules on Skin Epithelialization

    Författare :Sofi Forsberg; Ola Rollman; Arne Östman; Anders Vahlquist; Eva Hagforsen; Gunnar Kratz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatology and venerology; Dermatologi och venerologi;

    Sammanfattning : Human skin forms a biologically active barrier and maintains vital protective functions through continuous regeneration of cells within its outermost layer, the epidermis. In healthy skin, renewal of epithelial cells is a tightly regulated process in which the epidermal growth factor receptor (EGFR or HER1) and its various ligands are involved. LÄS MER

  3. 12. Prognostic biomarkers in upper gastrointestinal adenocarcinoma

    Författare :CHARLOTTA HEDNER; Tumörmikromiljö; []
    Nyckelord :;

    Sammanfattning : Estimates indicate that the global cancer burden may be ever-increasing. Gastric cancer is one of the major cancer forms. Despite its declining incidence, the high mortality of gastric cancer makes it the third most common cause of cancer-related death. Esophageal cancer is less common, but the incidence is increasing in parts of the world. LÄS MER

  4. 13. Prognostic factors in periampullary adenocarcinoma. A retrospective study over an 11 year period

    Författare :Jacob Elebro; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periampullary adenocarcinoma; Pancreatic cancer; bile duct cancer; ampullary adenocarcinoma; duodenal adenocarcinoma; Immunohistochemestry; prognosis;

    Sammanfattning : Periampullary adenocarcinoma, including pancreatic cancer, has a poor prognosis that has not improved in the last decades. Therefore, in order to find more effective treatment regimens, it is necessary to gain more insight into the biology and clinical behaviour of these tumours. LÄS MER

  5. 14. Improvements and Applications of in situ Proximity Ligation Assays

    Författare :Karin Grannas; Ola Söderberg; Christer Wingren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molekylär medicin; Molecular Medicine;

    Sammanfattning : The cells building up the human body is in constant communication with each other. This communication is done through large complex networks of signaling pathways for inter- and intracellular signal transduction. The signaling activity regulates many important processes, for example cell death, proliferation and differentiation. LÄS MER

  7. 15. Estrogen receptor β signalling in mammary epithelial and breast cancer cells

    Författare :Karolina Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens are key players in the etiology and progression of breast cancer, and mediate their effects through the estrogen receptors (ERα and ERβ). ERα plays important roles in proliferation and progression of breast cancer, whereas a distinct function of ERβ in the initiation and development of breast cancer is not yet clearly established. LÄS MER