Sökning: "HER-2"

Visar resultat 11 - 15 av 16 avhandlingar innehållade ordet HER-2.

  1. 11. Radionuclide targeting with particular empahsis on urinary bladder carcinoma

    Författare :Anna Sjöström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi; Oncology; Onkologi; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Sammanfattning : The incidence of urinary bladder carcinoma is increasing and many patients die every year of this disease despite assumed radical therapy. Thus, there is a need for improved methods of diagnosis and therapy. LÄS MER

  3. 12. Angiogenesis Related Markers In Non-Small Cell Lung Cancer

    Författare :Daniel Brattström; Ola Brodin; Gunnar Wagenius; Torgny Rasmusen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Lung cancer; NSCLC; Therapy; Angiogenesis; VEGF; bFGF; Microvessel density; Survival; Onkologi; Oncology; Onkologi;

    Sammanfattning : This thesis investigated the predictive and the prognostic powers of angiogenesis related markers in both operable and inoperable non-small cell lung cancer (NSCLC) patients.In the first and second study, we investigated the serological fractions of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in 2 cohorts of patients with either operable or inoperable NSCLC. LÄS MER

  4. 13. Recognition by and escape from CD8+ T cell immune surveillance in cancer bearing hosts

    Författare :Koji Kono; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : CD8+ T cells ( TCD8+ ) can specifically recognize tumor cells through MHC class I molecules associated with peptides that are 8-l0 amino acid residues long. In recent years, a number of tumor-associated antigens, or their epitopes, have been identified and characterized with the advent of new methods in molecular biology and in peptide isolation. LÄS MER

  5. 14. Human cytomegalovirus : from novel strain, miRNAs to interplay with breast cancer

    Författare :Abdul Aleem Mohammad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prevalence of human cytomegalovirus (HCMV) ranges from 40% to 100% worldwide. A primary HCMV infection results in a lifelong latent or persistent infection. LÄS MER

  7. 15. Analytical strategies for identifying relevant phenotypes in microarray data

    Författare :Kristian Wennmalm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : With microarray technology, the transcription thousands of genes can be determined simultaneously. The large number of genes, often assessed in a relatively small number of samples, presents a challenge. The risk of making false positive discoveries is substantial, and making biological sense of hundreds of identified genes is difficult. LÄS MER