Sökning: "HCV"

Visar resultat 16 - 20 av 95 avhandlingar innehållade ordet HCV.

  1. 16. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals

    Författare :Midori Kjellin; Johan Lennerstrand; Nina Weis; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C; HCV; DAA; RAS; resistance-associated substitution; baseline resistance; NS5A; NS3; SVR; Medical Virology; Medicinsk virologi; Mikrobiologi; Microbiology; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. LÄS MER

  2. 17. GB virus C/hepatitis G virus infection: clinical, histological and epidemiological aspects

    Författare :Per Björkman; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endoscopy; nosocomial; sexual transmission; parenteral transmission; blood donor; ALT; liver disease; hepatitis; GBV-C HGV; HCV; Infections; Infektioner;

    Sammanfattning : GBV-C/HGV is a blood-borne virus related to the hepatitis C virus. We studied GBV-C/HGV infection in different populations, its transmission, and its association with liver disease. GBV-C/HGV viraemia was detected by PCR in 19/576 blood donors. Donors with normal and elevated ALT levels had similar rates of viraemia (1. LÄS MER

  3. 18. Immune modulation in chronic HBV and HCV infection

    Författare :Catharina Hultgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HBV; HBeAg; HCV; NS3; chronic infection; humoral cellular immune response; Th1 Th2 cells; proliferative response;

    Sammanfattning : Chronic viral hepatitis is a major health problem worldwide. The two major viral causes for chronic hepatitis are the hepatitis B (HBV) and C viruses (HCV). HBV is a DNA virus with a rather limited genetic variability whereas HCV is an RNA virus with a high genetic variability. LÄS MER

  4. 19. HIV/HCV co-infection in Sweden : epidemiology, HCV treatment and the importance of IL28B gene polymorphism

    Författare :Jenny Stenkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Liver disease, mainly due to hepatitis C virus (HCV) infection, is a leading cause of death in HIV positive patients with access to antiretroviral therapy (ART). HCV treatment, which can prevent long-term complications of HCV infection, is available. Despite this, only a minority of HIV/HCV co-infected patients initiate HCV treatment. LÄS MER

  5. 20. HIV-1/HCV co-infection : immunity and viral dynamics

    Författare :Karolin Falconer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) are the agents behind two viral epidemics causing huge morbidity and mortality worldwide. HCV infection is a leading cause of end-stage liver disease. LÄS MER