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  1. 1. On the association between panic disorder and autonomic regulation – With special focus on the roles of respiration and on the catechol-O-methyltransferase gene

    Författare :Kristina Annerbrink; Göteborgs universitet; []
    Nyckelord :panic disorder; serotonin; respiration; polymorphism; COMT Val158Met; HCRTR2 G1246A; blood pressure; anthropometry;

    Sammanfattning : Background and aims: Panic disorder is a psychiatric disorder characterized by sudden attacks of intense anxiety. It displays a lot of features suggesting that it may be associated with an underlying aberration in the autonomic regulation of heart activity and respiration: i) the attacks are often characterized by respiratory symptoms and symptoms from the heart, ii) the attacks can be elicited by respiratory stimulants, iii) between attacks, patients with panic disorder often display enhanced respiratory variability and reduced heart rate variability, and iv) patients with panic disorder display enhanced prevalence of respiratory disorders and enhanced mortality in cardiovascular disease. LÄS MER