Sökning: "HBcAg"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet HBcAg.

  1. 1. Functional role of T-cell activation in viral hepatitis

    Författare :Jessica Nyström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HBV; HCV; HBcAg; NS3 4A; HBsAg; T-cells;

    Sammanfattning : Hepatitis B and C (HBV, HCV) constitute global health problems and there are approximately 350 million chronically HBV infected people around the world, most of them are found in East and South East Asia and Africa. Worldwide there are 170 million HCV infected individuals with the highest prevalence seen in Egypt. LÄS MER

  3. 2. Characterisation of the interaction between the Hepatitis B virus core antigen and B cells

    Författare :Una Lazdina; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HBcAg; B cells; B cell antigen receptor; co-stimulatory molecules; cytokines; T helper cells; cytotoxic T cells;

    Sammanfattning : The Hepatitis B virus (HBV) is a major cause of severe human liver disease globally. There are around 350 million persistent HBV carriers with a risk of development of liver disease including cirrhosis and hepatocellular carcinoma. LÄS MER

  4. 3. Improving immunogenicity of hepatitis B and C viral proteins for vaccine design

    Författare :Antony Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The hepatitis B and C virus (HBV, HCV) both presents a global health challenge, with an estimated 350 million individuals chronically infected with HBV and over 200 million infected with HCV. Reported cases of HBV and HCV have declined significantly due to screening of blood products and the availability of HBV vaccination. LÄS MER

  5. 4. Development of vaccines and mouse models for chronic hepatitis C virus infection

    Författare :Sepideh Levander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic hepatitis C virus (HCV) infection is a major causative agent for severe liver disease and cancer worldwide. Globally, it is estimated that approximately 185 million people are infected with HCV and 130-170 million of these are chronic carriers of the virus (1, 2). LÄS MER

  7. 5. Viral and host determinants in hepatitis B

    Författare :Hossein Sendi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The outcome of hepatitis B infection is highly variable, ranging from acute disease resulting in the elimination of infection to persistent infection that can lead to cirrhosis or hepatocellular carcinoma. The factors determining the outcome in an individual are not fully known but may be classified into viral and host factors. LÄS MER