Sökning: "Guy Lloyd"
Hittade 3 avhandlingar innehållade orden Guy Lloyd.
1. Mechanical and histological disturbances in advanced heart failure and cardiac transplantation
Sammanfattning : The general purpose of this thesis is to establish capability and accuracy of speckle tracking echocardiography (STE) in assessing left atrial (LA), left ventricular (LV) and right ventricular (RV) function and their correlation with myocardial fibrosis, filling pressure and clinical outcomes in advanced heart failure (HF) patients before and after heart transplantation (HT).I demonstrated that HT recipients had impaired LV twist dynamics in the form of reduced rotation twist angle and untwist rate but time to peak twist was not different from the age matched controls and other cardiac surgical patients. LÄS MER
2. Synthesis of Novel Chiral Bicyclic Ligands and their Application in Iridium-Catalyzed Reactions
Sammanfattning : The synthesis of 2-aza-norborane derivatives is presented. The use of these compounds in preparation of Ir catalysts for asymmetric hydrogenations is described. The evaluation and optimization of the catalysts as well as the mechanistic aspects of the catalytic process are discussed. LÄS MER
3. Development of highly modular ligands for use in asymmetric transition-metal catalyzed reactions
Sammanfattning : The synthesis and evaluation of ligands for use in asymmetric transition metal catalyzed reactions is a widely used concept to achieve improved enantioselectivity in a variety of different transformations. The present thesis decribes the synthesis of a number of different oxazoline-based ligands and their use in titanum-catalyzed addition of diethyl zinc to aliphatic and aromatic aldehydes. LÄS MER