Sökning: "Gut regulatory peptides"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Gut regulatory peptides.

1. 1. Gut peptides in gastrointestinal motility and mucosal permeability

   Författare :Md. Abdul Halim; Webb Dominic-Luc; Per M Hellström; Lars Fändriks; Uppsala universitet; []
   Nyckelord :Gut regulatory peptides; Neuropeptides; Gastrointestinal mucosal permeability; Gastrointestinal motility; GLP-1; NPS; ROSE-010;

   Sammanfattning : Gut regulatory peptides, such as neuropeptides and incretins, play important roles in hunger, satiety and gastrointestinal motility, and possibly mucosal permeability. Many peptides secreted by myenteric nerves that regulate motor control are also produced in mucosal epithelial cells. LÄS MER

3. 2. Gastric Bypass in Morbid Obesity : Postoperative Changes in Metabolic, Inflammatory and Gut Regulatory Peptides

   Författare :Camilla Holdstock; Britt Edén Engström; Anders Karlsson; Per Hellström; Uppsala universitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; gastric bypass; morbid obesity; ghrelin; C-reactive protein; pancreatic polypeptide; peptide YY; glucagon-like peptide-1; Medicine; Medicin;

   Sammanfattning : This thesis examines the effect of surgical weight loss on gut and adipose tissue peptides involved in appetite regulation and energy homeostasis in morbidly obese humans. Roux-en-Y gastric bypass (RYGBP) is the gold standard operation used for effective long-term weight loss and improved health. LÄS MER

4. 3. Isoform-specific regulation of Drosophila gut immunity and regeneration by the POU/Oct transcription factor Nub/Pdm1

   Författare :Xiongzhuo Tang; Ylva Engström; Tony Ip; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; POU; Nubbin; Drosophila; intestinal stem cell; epithelium regeneration; midgut; mitosis; Antimicrobial peptides; innate immunity; NF-κB; bacterial infection; transcriptional regulation; homeostasis; Molecular Biology; molekylärbiologi;

   Sammanfattning : Innate immune reactions protect organisms against a variety of infections.  In metazoans, these reactions involve both cellular and humoral responses. The immune responses have to be well-tuned, as excessive immune activation is associated with tissue-specific pathologies. LÄS MER

5. 4. Regulatory mechanisms involved in pathoadaptation of extraintestinal pathogenic Escherichia coli

   Författare :Nikola Zlatkov; Bernt Eric Uhlin; Åke Forsberg; Sun Nyunt Wai; Eliora Ron; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ExPEC; PAIs; pathoadaptation; citrate; metabolism; filamentation; toxins; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

   Sammanfattning : Establishment of commensal bacteria within a new niche of their host usually promotes the transition from commensalism to pathogenicity. Extraintestinal Pathogenic Escherichia coli (ExPEC) represent different pathovars with biphasic lifestyle – they can reside in the gut as commensals or they can escape and cause diseases elsewhere in the human body. LÄS MER

7. 5. Oral tolerance mechanisms and the role of the microbiota

   Författare :Sofia M Östman; Göteborgs universitet; []
   Nyckelord :;

   Sammanfattning : The hygiene hypothesis state that microbial stimulation is necessary to fully activate and mature the immune system and to sustain tolerance mechanisms. Oral tolerance maintains immune homeostasis in the gut and prevents adverse reactions towards the comensal flora and Ags from the food and thus protects from development of allergies and inflammatory bowel diseases (IBD). LÄS MER