Sökning: "Gut bacteria"

Visar resultat 16 - 20 av 136 avhandlingar innehållade orden Gut bacteria.

  1. 16. galactmannan degradation by fungi and gut bacteria : structural enzymology and fine -tuned substrate specifcity

    Författare :Sumitha Krishnaswamyreddy; Biokemi och Strukturbiologi; []
    Nyckelord :fine-tuned substrate specificity; β-mannanase; β-mannosidases; synergy; α-galactosidases; mannan converison in gut; transglycosylation; polysaccharide utilisation locus; phylogenetic analysis; MALDI-TOF MS;

    Sammanfattning : AbstractThe degradation of plant based β-mannan polysaccharides represents one of the many challenges efficiently tackled by microorganisms living in different habitats. In this thesis, glycoside hydrolases (GHs) involved in mannan degradation from two different organisms, Aspergillus nidulans (paper I and II) and Bacteroides ovatus (paper III and IV) were studied. LÄS MER

  3. 17. The Gut Bacterial Flora - Focus on Early Life and Physiological Traits

    Författare :Caroline Linninge; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gut microbiota; atopic eczema; inflammation; bacterial diversity; Escherichia coli; Lactobacillus plantarum; molecular-genetic methods;

    Sammanfattning : The gastrointestinal tract of the foetus is considered sterile but during vaginal birth the neonate comes into contact with bacteria from the maternal vaginal and intestinal microbiota. The main focus of this doctoral thesis was to elucidate the initial bacterial ecosystem in newborns and to relate microbial perturbations to physiological traits. LÄS MER

  4. 18. Strategies for the Discovery of Carbohydrate-Active Enzymes from Environmental Bacteria

    Författare :Johan Larsbrink; Vincent Bulone; Harry Brumer; Birte Svensson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CAZyme discovery; xyloglucan; polysaccharide-utilisation locus; microbiota; α-xylosidase; GH31; transglucosidase; human gut; SRA - Molekylär biovetenskap; SRA - Molecular Bioscience;

    Sammanfattning : The focus of this thesis is a comparative study of approaches in discovery of carbohydrate-active enzymes (CAZymes). CAZymes synthesise, bind to, and degrade all the multitude of carbohydrates found in nature. LÄS MER

  5. 19. Integrative analysis of multi-omics data reveals links between human diseases and the gut microbiota

    Författare :Peishun Li; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; multi-omics; gut microbiota; metabolic modeling; type 2 diabetes; machine learning; osteoporosis; metabolomics;

    Sammanfattning : The gut microbiota plays a critical role in human diseases, including type 2 diabetes (T2D) and osteoporosis. Especially, probiotics have been suggested to provide potential intervention strategies for improving human health. LÄS MER

  7. 20. Gut microbes and the developing brain

    Författare :Tim Arentsen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The discovery that commensal gut microbiota can influence host development and physiology beyond the gastrointestinal (GI) tract has triggered a paradigm shift in our conceptualization of the origin of human diseases. A growing body of preclinical research has demonstrated that gut microbiota exert a modulatory role on the development and function of brain circuits involved in motor control, emotion and cognition. LÄS MER