Sökning: "Gunnar Nilsson"

Visar resultat 21 - 25 av 34 avhandlingar innehållade orden Gunnar Nilsson.

  1. 21. Regulation of Mast Cell Survival

    Författare :Christine Möller; Gunnar Nilsson; Alf Grandien; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; mast cell; A1; Bfl-1; Bim; Bcl-2 family members; basophil; SCF; forkhead; survival; Patologi; Pathology; Patologi;

    Sammanfattning : Mast cells are long-lived effector cells of importance for both acute and chronic inflammations. Mast cells can be activated in many different ways, leading to the release of inflammatory mediators. In contrast to most other inflammatory cells, activated mast cells have the capacity to recover, regranulate and thereby be activated again. LÄS MER

  3. 22. Exploring eicosanoids as biomarkers in severe chronic rhinosinusitis with nasal polyps

    Författare :Axel Nordström; Maria Kumlin; Marie Svedberg; Mattias Jangard; Michael Ryott; Gunnar Nilsson; Sophiahemmet Högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Chronic rhinosinusitis (CRS) is one of the most common inflammatory chronic conditions, leading to a persistent nasal congestion, nasal discharge, and a loss of smell. Despite sinus surgery and frequent use of oral corticosteroids, a large proportion of individuals with CRS are difficult to treat and have recurrent inflammation. LÄS MER

  4. 23. Mast Cell Migration in Inflammatory Diseases

    Författare :Niclas Olsson; Gunnar Nilsson; Jaroslaw Dastych; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Mast cells; chemotaxis; inflammation; Patologi; Pathology; Patologi;

    Sammanfattning : Mast cells (MCs) are forceful multifunctional effector cells of the immune system. MCs are normally distributed throughout connective and mucosal tissues, but in several pathological conditions accumulation of MCs occur. LÄS MER

  5. 24. Assessment of therapeutic targets in experimental models of Myc-induced lymphoma

    Författare :Linus Plym Forshell; Jonas Nilsson; Lars-Gunnar Larsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Myc; Decitabine; Pim kinase; RCAS-tva; Neurobiology; Neurobiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The Myc transcription factor activates expression of genes that promote cellular functions such as proliferation and cell growth. The deregulated Myc expression, characteristic for the tumor cell, also activates apoptosis, which selects for additional genetic changes deactivating the induced cell death. LÄS MER

  7. 25. Towards comprehensive cellular atlases : High-throughput cell mapping by in situ sequencing

    Författare :Xiaoyan Qian; Mats Nilsson; Gunnar von Heijne; Anthony Zador; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Spatially resolved transcriptomics; in situ sequencing; cell type; spatial analysis; Biochemistry; biokemi;

    Sammanfattning : With recent technological advancements in single-cell biology, many aspects of individual cells are characterized with unprecedented resolution and details. Cell types in human and model organisms are redefined, and multiple organ-wide atlases are proposed to integrate different types of data to provide a comprehensive view of biological systems at cellular resolution. LÄS MER