Sökning: "Granulocyte-macrophage colony-stimulating factor GM-CSF"

Visar resultat 16 - 20 av 21 avhandlingar innehållade orden Granulocyte-macrophage colony-stimulating factor GM-CSF.

  1. 16. Delivery of DNA vaccines against cancer

    Författare :Anna-Karin Roos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA vaccine; prostate-specific antigen; immunotherapy; prostate cancer; electroporation;

    Sammanfattning : DNA vaccines against cancer have shown promising results in animal models. Efficient antigenspecific T cell responses and tumor protection have been demonstrated after vaccination with DNA encoding tumor antigens in mice. LÄS MER

  3. 17. Studies of T cells in health and disease : receptor usage and cytokine expression

    Författare :Eva Halapi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :T cell receptor; oligoclonal expansion Tumour-infiltrating Iymphocyte; Ovarian carcinoma; Interleukin 10; Multiple Myeloma; Systemic vasculitis; HLD DR0401*CDR3; HIV-I;

    Sammanfattning : T Iymphocytes are crucial components for the initiation and maintenance of an immune response. To identify and characterize different T cells and their antigen specific receptors has important bearing for the understanding of underlying mechanisms in immunopathological processes and also to allow for the design of therapeutic therapies to be used for modulation of immune responses. LÄS MER

  4. 18. Vaccine strategies based on mycobacterial heat shock protein 65

    Författare :Maria Sundbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mycobacteria; DNA vaccination; Hsp65; T cells; CD8 T cell epitopes;

    Sammanfattning : Mycobacteria can infect macrophages and dendritic cells (DC), where they reside inside the endosomal compartment. The importance of CD4+ T cells in protective immunity against mycobacteria and other intracellular pathogens is well established, and for a long time these cells were thought to be the major defense in controlling an infection. LÄS MER

  5. 19. Immune and gene therapies for cancer and infectious diseases

    Författare :Jehad Charo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Immunotherapy; gene therapy; cytokines; MHC-1; tucaresol; EBV; mycobacteria; HER-2; Tumors;

    Sammanfattning : Annually more than 20 million deaths are globally caused because of infections or cancer. This accounts for 41.5% of annual deaths. New techniques are supposed to constitute our tools in the fight against these types of deaths. LÄS MER

  7. 20. Seminal Influence on the Oviduct : Mating and/or semen components induce gene expression changes in the pre-ovulatory functional sperm reservoir in poultry and pigs

    Författare :Mohammad Atikuzzaman; Heriberto Rodriguez-Martinez; Dominic Wright; Karl-Eric Magnusson; Maria Jenmalm; Matthias Laska; Patrice Humblot; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Seminal plasma; proteome peptidome; oviduct; gene expression; chicken; pig;

    Sammanfattning : Internal fertilization occurs in birds and eutherian mammals. Foetal development, however, is either extra- respectively intra-corpore (egg vs uterus). LÄS MER