Sökning: "Grammatiki Fotaki"

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1. 1. Allogeneic dendritic cells as adjuvants in cancer immunotherapy

   Författare :Grammatiki Fotaki; Magnus Essand; Alex Karlsson-Parra; Di Yu; Tanja de Gruijl; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allogeneic dendritic cells; immune primer; adjuvant; adenoviral vector; cancer immunotherapy; tumor microenvironment; Klinisk immunologi; Clinical Immunology;

   Sammanfattning : In recent years, immunotherapeutic approaches have achieved remarkable successes through checkpoint blockade antibodies, advances in the use of chimeric antigen receptor (CAR) T cells and new insights into the immunosuppressive role of the tumor microenvironment (TME). Through the advances, the role of cancer vaccines based on ex vivo manipulated autologous dendritic cells (DC) has been challenged. LÄS MER