Sökning: "Gonçalo De Sá E Sousa De Castelo-branco"

Hittade 1 avhandling innehållade orden Gonçalo De Sá E Sousa De Castelo-branco.

  1. 1. Wnt signalling in the development of ventral midbrain dopaminergic neurons

    Författare :Gonçalo de Sá e Sousa de Castelo-Branco; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dopaminergic Neuron; Ventral Midbrain Development; Writs; Dickkopf; beta-catenin; GSK-3beta; Stem Cells; Neural Precursors;

    Sammanfattning : Dopaminergic (DA) neurons in the ventral midbrain (VM) are one of the major cell types lost in Parkinson's disease (PD). Proof-of-principle exists for cell replacement therapies for PD, but wider application is halted by the unavailability of abundant sources of DA neurons. Stem cells might constitute one of these sources. LÄS MER