Sökning: "Glycosylated analysis"

Visar resultat 21 - 25 av 39 avhandlingar innehållade orden Glycosylated analysis.

  1. 21. Clinical studies on α1-acid glycoprotein glycosylation - with focus on fucose

    Författare :Ingvar Rydén; Joyce Carlson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : α1-Acid glycoprotein (AGP, orosomucoid) is a heavily glycosylated protein found in blood plasma in all humans. AGP is one of the major acute phase proteins, and its concentration is frequently measured in clinical laboratories as a marker for inflammatory disease. LÄS MER

  3. 22. Colon cancer specific cytochrome P450 2W1 : polymorphism, membrane topology and endogenous roles in development

    Författare :Jia Guo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cytochrome P450 2W1 (CYP2W1) belongs to a family of drug metabolizing monooxygenases with an unidentified yet endogenous function. CYP2W1 expression pattern has characteristic features of oncofetal genes. Previous studies have shown significant levels of CYP2W1 protein in 30% of human colon cancers and in 50% of corresponding liver metastases. LÄS MER

  4. 23. Mass spectrometry for comparative proteomics of degenerative and regenerative processes in the brain

    Författare :Carina Sihlbom; Göteborgs universitet; []
    Nyckelord :glycoproteomics; quantitative proteomics; glycoprotein; protein quantification; glycosylation; Fourier transform ion cyclotron mass spectrometry; cerebrospinal fluid; Alzheimer s disease; neurodegeneration; neuroregeneration; hippocampus; astrocytes; brain injury; 14-3-3 protein; isoform;

    Sammanfattning : Biological processes involve changes at the protein level. Proteomics aims to determine protein changes from a normal state, to measure for instance recovery or disease progression. Mass spectrometry is the most important tool for identification of proteins and determination of post-translational modifications such as glycosylation. LÄS MER

  5. 24. Insulin-like growth factor binding protein-3 : structure and function

    Författare :Maria Ahlsén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Insulin-like growth factor (IGF) -I and -II share structural homology with insulin. Their receptors and intracellular signaling are similar. Consequently, the biological actions of IGFs and insulin are overlapping. Insulin is secreted on demand depending on e. LÄS MER

  7. 25. Plasma membrane arabinogalactan proteins

    Författare :Lars Snogerup; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; arabinogalactan protein plant development cell-cell interaction plasma membrane; Plant biochemistry; Växtbiokemi;

    Sammanfattning : Arabinogalactan proteins (AGPs) are proteoglycans found at the outer side of the plasma membrane and in the extracellular matrix of plants. To be able to study the plasma membrane bound AGPs, a method using SDS-agarose gel electrophoresis (SDS-AGE) was developed to overcome the problems associated with electrophoretic separation of highly glycosylated proteins. LÄS MER