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Visar resultat 1 - 5 av 20 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. The advantages of being small : Glycosyltransferases in many dimensions and glycolipid synthesis in Mycoplasma Pneumoniae

    Författare :Maria Rosén Klement; Åke Wieslander; Christelle Breton; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Glycosyltransferase; lipid; membrane; glycolipid; ACC; PLS-DA; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : The synthesis and breakdown of sugars is one of the most important functions in Nature. Consequently, sugar structures are used both as energy storage and as building blocks to stabilise and protect the cell. The formation of these structures is performed by glycosyltransferases (GT), an enzyme group structurally conserved within all kingdoms. LÄS MER

  3. 2. Glycoconjugates : Solid-phase synthesis and biological applications

    Författare :Fredrik Wallner; Mikael Elofsson; Jan Kihlberg; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Glycoconjugate; Glycolipid; Solid-phase synthesis; Glycosylation; Gel-phase 19F-NMR spectroscopy; Fluorinated linker; Carbohydrat array; CD1; Organic chemistry; Organisk kemi;

    Sammanfattning : Glycoconjugates are biologically important molecules with diverse functions. They consist of carbohydrates of varying size and complexity, attached to a non-sugar moiety as a lipid or a protein. Glycoconjugate structures are often very complex and their intricate biosynthetic pathways makes overexpression difficult. LÄS MER

  4. 3. Plant pathogen defense: Signalling, resistance and cell death

    Författare :Oskar N. Johansson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pseudomonas; cell death; pathogens; plant defense; hypersensitive response; glycolipid; reactive oxygen species; blumeria graminis; erysiphe pisi;

    Sammanfattning : Pathogenic microorganisms are present everywhere in nature and infect both animals and plants. Phytopathogenic microorganisms cause diseases on plants, and are responsible for crop loss amounting in the order billions of dollars annually. LÄS MER

  5. 4. Chemical basis of ABO subgroups

    Författare :Lola Svensson; Göteborgs universitet; []
    Nyckelord :ABO; subgroups; glycolipid; para-Forssman; Forssman; Forssman synthetase;

    Sammanfattning : Despite the ABO histo-blood group system being the most biologically significant in humans the chemical structures that define its various phenotypes still remain largely unresolved. Like all blood group systems there is a significant range in the amount of antigen present on the red cells of an individual and there exists a range of so-called “weak” phenotypes represented by decreasing expression of A or B antigens. LÄS MER

  7. 5. Functional dynamics of glycosyltransferases : Solution-state NMR studies of peripheral membrane proteins involved in glycolipid biosynthesis in bacteria

    Författare :Joan Patrick; Lena Mäler; Magnus Wolf-Watz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik;

    Sammanfattning : Antibiotic resistance is an existential threat enabled by bacterial adaptation and fuelled by inappropriate use of medication. The ensuing shortage of effective treatments has led to a rise in deaths linked to resistant bacterial pathogens. LÄS MER