Sökning: "Glutathione S-transferase"

Visar resultat 1 - 5 av 38 avhandlingar innehållade orden Glutathione S-transferase.

  1. 1. The significance of glutathione S-transferases in biochemical toxicology : kinetic and binding studies designed to establish a mechanism of action of glutathione S-transferase A from rat liver

    Författare :Inga Jakobson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  3. 2. Diet, lifestyle, antioxidants, and biomarkers of cancer risk - an epidemiological report from the Malmö Diet and Cancer cohort

    Författare :Peter Wallström; Nutritionsepidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; cancer; Public health; epidemiology; Folkhälsa; epidemiologi; cancerology; Cytologi; oncology; Cytology; Alcohol; Obesity; Smoking; Autoantibodies; Glutathione S-transferase; Oxidative stress; Vitamin E; Carotene; Body composition; Vegetables; Fruits; Cross-sectional; Adult; Diet surveys;

    Sammanfattning : This thesis examines associations between a number of epidemiological or biological markers of cancer risk and oxidative stress, in order to achieve a better understanding of how diet, lifestyle, and genetic factors contribute to the occurrence of oxidative stress. Data from the Malmö Diet and Cancer (MDC) cohort was used. LÄS MER

  4. 3. Isolation and characterization of glutathione S-transferases from various animal sources

    Författare :Claes Guthenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : In the present investigation several forms of glutathione S-transferase were found in preparations of rat liver, rat lung, adult human liver, fetal human liver and whole earthworms. Human placenta, however, appeared to contain only one form of glutathione S-transferase. LÄS MER

  5. 4. Microsomal glutathione transferase : studies on the kinetic mechanism, species variety, binding properties and substrate measurement

    Författare :Tie-Hua Sun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Microsomal glutathione transferase (MGST) is a membrane bound detoxification enzyme, which has been purified from different species including rat, mouse, human, frog, and fish. The rat MGST1 is localized predominantly in the liver microsomes and the outer mitochondrial membrane. LÄS MER

  7. 5. Oxidative damage and the DNA glycosylase MutYH

    Författare :Kristina Jansson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Oxidative damage; 8-oxo-7; 8-dihydro-2′-deoxyguanosine; Base excision repair; DNA glycosylase; Mismatch repair; DNA damage checkpoint; 9-1-1 complex; Glutathione-S-transferases; Colon cancer.;

    Sammanfattning : The DNA glycosylase MutYH is highly conserved throughout evolution, and homologs are found in most eukaryotes and prokaryotes examined. MutYH functions as a base excision repair DNA glycosylase that excises adenines misincorporated opposite 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), one of the most stable products of oxidative DNA damage. LÄS MER