Sökning: "Glucose levels"

Visar resultat 1 - 5 av 575 avhandlingar innehållade orden Glucose levels.

  1. 1. Glucose and lipid metabolism in insulin resistance an experimental study in fat cells

    Detta är en avhandling från Umeå : Folkhälsa och klinisk medicin

    Författare :Jonas Burén; Umeå universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; adipocyte; insulin resistance; type 2 diabetes; insulin signalling; glucose uptake; insulin; glucose; dexamethasone; insulin receptor substrate; protein kinase B; GLUT4; lipoprotein lipase; Folkhälsomedicin; MEDICINE Social medicine Public health medicine research areas; MEDICIN Socialmedicin Folkhälsomedicinska forskningsområden; medicin; Medicine;

    Sammanfattning : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. LÄS MER

  2. 2. Oxidative stress and inflammation as a response to glucose exposure and dialysis

    Detta är en avhandling från Department of Nephrology, Lund University

    Författare :Anna Bryland; Lunds universitet.; Lund University.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose; glucose degradation products; dialysis; diabetes; oxidative stress; inflammation; endothelial dysfunction;

    Sammanfattning : Abstract: The main player of this thesis is glucose, both on a cellular level and with a clinical approach. Too much or wrongly handled glucose contributes to increased inflammation and oxidative stress, which is reinforced by the negative influences of uraemia and dialysis treatment. LÄS MER

  3. 3. Glucose- and hypoxia-regulated insulin gene expression

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Linda Tillmar; Uppsala universitet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; islet; beta-cell; insulin; mRNA stability; PTB; glucose; hypoxia; mTOR; p70s6k; ceramide; redox; ROS; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Although extensively studied, there are still many unanswered questions regarding the exact regulation of insulin gene expression. This is important to further investigate since it will hopefully help us understand the pathophysiology of some types of diabetes. LÄS MER

  4. 4. Fat cell insulin resistance an experimental study focusing on molecular mechanisms in type 2 diabetes

    Detta är en avhandling från Umeå : Folkhälsa och klinisk medicin

    Författare :Frida Renström; Umeå universitet.; [2007]
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; adipocyte; insulin signaling; insulin; glucose; IRS-1; glucose uptake; insulin resistance; typ 2 diabetes; serum; VETERINARY MEDICINE Medicine; VETERINÄRMEDICIN Medicin;

    Sammanfattning : The aim of the present thesis was to further increase our understanding of mechanisms contributing to and maintaining cellular insulin resistance in type 2 diabetes (T2D). For this reason, the effects of high glucose and insulin levels on glucose transport capacity and insulin signaling, with emphasis on insulin receptor substrate 1 (IRS-1) were assessed in fat cells. LÄS MER

  5. 5. Effects of acute metabolic interventions on hemodynamics, endothelial function and forearm glucose uptake

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Andreas Fugmann; Uppsala universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; Insulin; glucose; lipids; bloodflow; endothelium; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Hyperinsulinemia is known to augment endothelium-dependent.vasodilation (EDV). If physiological levels of insulin lead to peripheral, vasodilation and if this vasodilation is an independent determinant of skeletal muscle glucose uptake is however under debate. LÄS MER