Sökning: "Glomerular permeability"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Glomerular permeability.

  1. 1. Dynamics of the glomerular filtration barrier - Physiological and pathophysiological aspects

    Författare :Josefin Axelsson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Glomerular permeability; Microalbuminuria; Albumin; Ficoll; Sieving Coefficient; Rats;

    Sammanfattning : The dynamic properties of the glomerular filtration barrier (GFB) are of fundamental importance for the understanding of the physiology and pathophysiology of microalbuminuria and proteinuric diseases. In the studies of this doctoral thesis the properties of the rat glomerular filtration barrier were investigated under resting conditions and following a number of challenges using highly sensitive gel filtration chromatography (HPSEC) detection of FITC-Ficoll in serum and urine. LÄS MER

  3. 2. Properties of the glomerular endothelial cell surface layer in vitro and in vivo

    Författare :Vincent Fridén; Göteborgs universitet; []
    Nyckelord :Glomerular filtration; Glomerular endothelial cell surface layer; Proteinuria; Proteoglycans; glycocalyx; glycosaminoglycans; glomerular endothelial cells; permselectivity and glomerular endothelial cell coat;

    Sammanfattning : A healthy kidney produces final urine that is practically devoid of proteins and other physiologically important solutes. Tremendous amounts of fluid are filtered every day through the glomerular filtration barrier which is the actual sieving site in the kidney. LÄS MER

  4. 3. Physiological and morphological aspects of the glomerular barrier in health and disease. Results based on experimental studies in the rat

    Författare :Clara Hjalmarsson; Göteborgs universitet; []
    Nyckelord :glomerular permeability; isolated perfused kidney; charge; endothelial surface layer; glycocalyx; electron microscopy; orosomucoid; nephrotic syndrome; proteinuria;

    Sammanfattning : Tremendous amounts of fluid are filtered every day through the kidneys. The anastomosing capillary loops surrounded by Bowman s capsule, forming the glomerulus, function in accordance with the interplay between the hydrostatic and the colloid osmotic pressure. The result of the action of these mechanisms is the production of primary urine. LÄS MER

  5. 4. Properties of the endothelial cells and the glomerular barrier

    Författare :Jenny Sörensson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Capillary permeability; kidney glomerulus physiology; isolated perfused kidney; endothelium; orosomucoid; charge; horseradish peroxidase; inflammation; proteoglycan; cAMP.;

    Sammanfattning : The kidneys are vital organs that filter plasma to produce 180 liters of primary urine per day. Only 1% of this volume is excreted and the rest is reabsorbed. Naturally, such huge amounts of fluid must be well controlled to maintain the homeostasis, which is a prerequisite for life. LÄS MER

  7. 5. Experimental Studies on the Regulation of Glomerular Filtration Barrier Permeability In Vivo. Intra- and intercellular signaling mechanisms

    Författare :Julia Dolinina; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Nitric Oxide; Endothelin-1; Angiotensin II; TRPC5; TRPC6 channel;

    Sammanfattning : .... LÄS MER