Sökning: "Glomerular filtration"

Visar resultat 1 - 5 av 147 avhandlingar innehållade orden Glomerular filtration.

  1. 1. Dynamics of the glomerular filtration barrier - Physiological and pathophysiological aspects

    Författare :Josefin Axelsson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Glomerular permeability; Microalbuminuria; Albumin; Ficoll; Sieving Coefficient; Rats;

    Sammanfattning : The dynamic properties of the glomerular filtration barrier (GFB) are of fundamental importance for the understanding of the physiology and pathophysiology of microalbuminuria and proteinuric diseases. In the studies of this doctoral thesis the properties of the rat glomerular filtration barrier were investigated under resting conditions and following a number of challenges using highly sensitive gel filtration chromatography (HPSEC) detection of FITC-Ficoll in serum and urine. LÄS MER

  3. 2. Properties of the glomerular endothelial cell surface layer in vitro and in vivo

    Författare :Vincent Fridén; Göteborgs universitet; []
    Nyckelord :Glomerular filtration; Glomerular endothelial cell surface layer; Proteinuria; Proteoglycans; glycocalyx; glycosaminoglycans; glomerular endothelial cells; permselectivity and glomerular endothelial cell coat;

    Sammanfattning : A healthy kidney produces final urine that is practically devoid of proteins and other physiologically important solutes. Tremendous amounts of fluid are filtered every day through the glomerular filtration barrier which is the actual sieving site in the kidney. LÄS MER

  4. 3. Glomerular filtration rate in adults : a single sample plasma clearance method based on the mean sojurn time

    Författare :Margareta Gref; Kjell Karp; Börje Ljungberg; Umeå universitet; []
    Nyckelord :Clinical Physiology; klinisk fysiologi;

    Sammanfattning : Glomerular filtration rate (GFR) is a key parameter in evaluating kidney function. After a bolus injection of an exogenous GFR marker in plasma an accurate determination of GFR can be made by measuring the marker concentration in plasma during the excretion. LÄS MER

  5. 4. Physiological aspects of the glomerular filtration barrier

    Författare :Kristinn Sverrisson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Proteinuria is associated with progression of kidney disease and is an independent risk factor for cardiovascular morbidity and mortality. The pathophysiological alterations resulting in proteinuria are obscure, although proteinuria is often associated with pathological changes in the glomerular filtration barrier (GFB). LÄS MER

  7. 5. Functional Aspects of the Juxtaglomerular Apparatus : Control of Glomerular Filtration and Renin Release

    Författare :Johan Sällström; Erik Persson; Peter Hansell; Jürgen Schnermann; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : The juxtaglomerular apparatus (JGA) is a control unit of the kidney, that regulates glomerular filtration rate (GFR) and renin release, and hence extracellular volume and blood pressure. The tubuloglomerular feedback (TGF) mechanism is a negative feedback loop that regulates GFR. LÄS MER