Sökning: "Glomerular filtration barrier"
Visar resultat 6 - 10 av 28 avhandlingar innehållade orden Glomerular filtration barrier.
6. Analysis of Transvascular Transport Phenomena in the glomerular and peritoneal microcirculation
Sammanfattning : The current work is devoted entirely to the study of passive transport phenomena, or more specifically, the more simple diffusion, electric migration and filtration of solute matter and water over glomerular and peritoneal capillary walls. The driving forces behind such trans-capillary transport phenomena have long been assumed to be simple gradients of concentration, hydrostatic pressure and electric potential. LÄS MER
7. High-resolution Imaging of Cleared and Expanded Kidney Tissue Samples
Sammanfattning : The kidney is one of the most important and complex organs in the humanbody with the task of filtering hundreds of litres of blood daily. It is responsiblefor the salt and acid/base balance in the body, as well as secretinghormones important for red blood cell production and blood pressure regulation. LÄS MER
8. The expression of the structural proteins dendrin, Plekhh2 and Neph1 in the glomerular filtration barrier
Sammanfattning : Background: The podocytes are injured in many acquired glomerular diseases. This may present as proteinuria or morphological changes such as foot process effacement (FPE) or loss of podocytes in the urine. The exact mechanisms are still mainly unknown. LÄS MER
9. The expression of the structural proteins dendrin and Neph1 in the glomerular filtration barrier in proteinuria
Sammanfattning : Background: In the normal kidney, the glomerular filtration barrier successfully clears about one litre blood per minute. Damage to the filtration barrier might lead to protein leakage in the urine – proteinuria. The major ultra-structural finding in glomerular diseases with proteinuria is foot process effacement (FPE). LÄS MER
10. Permeability of the glomerular filtration barrier in relation to the size, shape, charge and deformability of the permeating molecules
Sammanfattning : Characterization of the glomerular filtration barrier is of fundamental importance for understanding the pathophysiology of proteinuric kidney diseases. Furthermore, it can be of key value in the understanding of microalbuminuria, which is often associated with endothelial dysfunction in conjunction with cardiovascular disease. LÄS MER