Sökning: "Glomerular filtration barrier"
Visar resultat 11 - 15 av 28 avhandlingar innehållade orden Glomerular filtration barrier.
11. The role of glycoproteins in glomerular pathophysiology
Sammanfattning : Chronic kidney disease (CKD) is increasing worldwide and has a prevalence of around 10%. With time patients are at risk of losing their renal function and will need dialysis or transplantation for survival. There are no specific treatments available and mechanisms behind the onset and progression of CKD are still not fully investigated. LÄS MER
12. Putting the pieces together : elucidation of podocyte biology in the homeostasis of the kidney filtration barrier
Sammanfattning : End-stage renal disease (ESRD) is a devastating condition that can only be treated with chronic dialysis or kidney transplantation. ESRD treatment costs account for up to 10% of healthcare budgets in the Western world. The 5-year survival for patients in dialysis is only about 40%. Glomerular disease processes are the main cause of ESRD. LÄS MER
13. Characterization of novel glomerular proteins : role in physiology and disease
Sammanfattning : Glomerular damage accounts for the majority of chronic kidney disease cases, the prevalence of which is dramatically escalating worldwide, mainly due to increase in diabetes and associated nephropathy. The costs for treatment of CKD represent an enormous burden to the health care system. LÄS MER
14. Characterization of novel genes of importance for renal glomerular function and disease
Sammanfattning : Glomerular kidney diseases are a major health care burden. The glomerular filtration barrier consists of three layers: the slit diaphragm that bridges the interlocking foot pro- cesses of the podocytes, the glomerular basement membrane and fenestrated endothelial cells. LÄS MER
15. Role of new podocyte-associated proteins in the renal ultrafiltration barrier
Sammanfattning : Chronic kidney disease (CKD) is a major health problem and an economical burden affecting people worldwide. The main causes of CKD are diabetes and hypertension and patient numbers keep increasing. LÄS MER