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Visar resultat 1 - 5 av 28 avhandlingar som matchar ovanstående sökkriterier.
1. Dynamics of the glomerular filtration barrier - Physiological and pathophysiological aspects
Sammanfattning : The dynamic properties of the glomerular filtration barrier (GFB) are of fundamental importance for the understanding of the physiology and pathophysiology of microalbuminuria and proteinuric diseases. In the studies of this doctoral thesis the properties of the rat glomerular filtration barrier were investigated under resting conditions and following a number of challenges using highly sensitive gel filtration chromatography (HPSEC) detection of FITC-Ficoll in serum and urine. LÄS MER
2. Properties of the glomerular endothelial cell surface layer in vitro and in vivo
Sammanfattning : A healthy kidney produces final urine that is practically devoid of proteins and other physiologically important solutes. Tremendous amounts of fluid are filtered every day through the glomerular filtration barrier which is the actual sieving site in the kidney. LÄS MER
3. Physiological aspects of the glomerular filtration barrier
Sammanfattning : Proteinuria is associated with progression of kidney disease and is an independent risk factor for cardiovascular morbidity and mortality. The pathophysiological alterations resulting in proteinuria are obscure, although proteinuria is often associated with pathological changes in the glomerular filtration barrier (GFB). LÄS MER
4. Experimental Studies on the Regulation of Glomerular Filtration Barrier Permeability In Vivo. Intra- and intercellular signaling mechanisms
Sammanfattning : .... LÄS MER
5. Characterization of novel podocyte proteins in the glomerular filtration barrier
Sammanfattning : The kidney is considered the most important organ of excretion eliminating the body from metabolic waste products. The nephron is the functional unit of the kidney, composed of a cluster of capillaries named glomerulus, and a tubular system. The blood is filtered in the glomerular capillaries across the glomerular filtration barrier. LÄS MER