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  1. 1. Immunogenetic studies in autoimmune endocrine diseases

    Författare :Giovanni Gambelunghe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type I Diabetes; LADA; Addison s disease; HLA; MICA; MICB; autoantibodies;

    Sammanfattning : Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterised by Tlymphocyte infiltration of islets of Langerhans with consequent destruction of beta cells. A permissive genetic background is required for the development of the islet autoimmune process. LÄS MER