Sökning: "Geodia barretti"

Hittade 4 avhandlingar innehållade orden Geodia barretti.

  1. 1. Bioactive Compounds from the Marine Sponge Geodia barretti : Characterization, Antifouling Activity and Molecular Targets

    Författare :Martin Sjögren; Lars Bohlin; Per Jonsson; Anna-Karin Borg-Karlsson; Uppsala universitet; []
    Nyckelord :Pharmacognosy; Geodia barretti; barettin; secondary metabolites; settling inhibition; Balanus improvisus; analogs; 5-HT; Farmakognosi;

    Sammanfattning : The marine sponge Geodia barretti produces a range of secondary metabolites. Two of these compounds were isolated and elucidated guided by their ability to inhibit settlement of cypris larvae of the barnacle Balanus improvisus. LÄS MER

  3. 2. Bioactive Compounds in the Chemical Defence of Marine Sponges : Structure-Activity Relationships and Pharmacological Targets

    Författare :Erik Hedner; Lars Bohlin; Per R Jonsson; Raffaele Riccio; Uppsala universitet; []
    Nyckelord :Pharmacognosy; 5-hydroxytryptamine; agelasine; agelasimine; antibacterial; antifouling; barettin; bromobenzisoxazolone barettin; cytotoxic; marine; secondary metabolite; sponge; Farmakognosi; Agelas; Geodia barretti;

    Sammanfattning : Marine invertebrates, in particular sponges, represent a source of a wide range of secondary metabolites, many of which have been attributed various defensive capabilities against environmental stress factors. In this thesis sponge-derived low-molecular peptide-like compounds and associated analogs are investigated for bioactivity and pharmacological targets. LÄS MER

  4. 3. Genomics and metabolomics in the North Atlantic deep-sea sponge Geodia barretti

    Författare :Karin Steffen; Paco Cárdenas; Ulf Göransson; Anders Backlund; Susanna López-Legentil; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; demosponge; whole genome sequencing; population genetics; peptide synthesis; Farmakognosi; Pharmacognosy;

    Sammanfattning : Sponges are among the earliest diverging taxa in the animal tree of life. They are sessile, filter-feeding animals found in marine and freshwater habitats. Many species are characterized by a close, specific and consistent association with microbes, mainly Bacteria and Archaea. LÄS MER

  5. 4. Analytical method development in liquid chromatography- mass spectrometry based metabolomics

    Författare :Ida Erngren; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Gérard Hopfgartner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Analytical pharmaceutical chemistry; metabolomics; liquid chromatography; mass spectrometry; hydrophilic interaction liquid chromatography; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Sammanfattning : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. LÄS MER