Sökning: "Genuttryck"

Visar resultat 1 - 5 av 88 avhandlingar innehållade ordet Genuttryck.

  1. 1. Eco-immunological studies of innate immunity in Mallards (Anas platyrhynchos)

    Författare :Anu S. Helin; Jonas Waldenström; Edwin Veldhuizen; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Avian β-defensins AvBDs ; Avian gene expression; Host-pathogen interactions; Innate immunity; Mallard Anas platyrhynchos ; Myxovirus resistance gene Mx ; Retinoic acid inducible gene 1 RIG-I ; Avian β-defensins AvBD ; Genuttryck; Gräsand Anas platyrhynchos ; Immunförsvar; Immungener; Myxovirus resistant gene Mx ; Patogen; Retinoic acid inducible gene 1 RIG-I ; Ecology; Ekologi;

    Sammanfattning : This thesis comprises two sections, both of which explore eco-immunology of the innate immune system of mallards (Anas platyrhynchos). The innate immune system serves a pivotal role as the first line of defense against invading pathogens, and is comprised of physical and chemical barriers. LÄS MER

  2. 2. Clinical aspects of molecular profiles in metastatic malignant melanoma

    Författare :Henrik Ekedahl; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanom; Prognos; BRAF; TERT; Genuttryck; Next generation sequencing; Melanoma; Prognosis; BRAF; TERT; Gene Expression; Next generation sequencing;

    Sammanfattning : Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. LÄS MER

  3. 3. Computational Models of Spatial Transcriptomes

    Författare :Ludvig Bergenstråhle; Joakim Lundeberg; Jens Lagergren; Ole Winther; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biotechnology; Bioteknologi;

    Sammanfattning : Spatial biology is a rapidly growing field that has seen tremendous progress over the last decade. We are now able to measure how the morphology, genome, transcriptome, and proteome of a tissue vary across space. LÄS MER

  4. 4. Novel resources enabling comparative regulomics in forest tree species

    Författare :David Sundell; Torgeir Hvidsten; Klaas Vandepoele; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Comparative genomics; Web resource; Wood development; RNA-Seq; Forestry; Lignocellulose; Regulomics; High-spatial resolution; Populus tremula; Picea abies; Orthology.; biology; biologi; molekylär bioteknik inst f nat vet biokemi ; molecular biotechnology dept of biochem ;

    Sammanfattning : Lignocellulosic plants are the most abundant source of terrestrial biomass and are one of the potential sources of renewable energy that can replace the use of fossil fuels. For a country such as Sweden, where the forest industry accounts for 10% of the total export, there would be large economical benefits associated with increased biomass yield. LÄS MER

  5. 5. Cardiac hypertrophy : transcription patterns, hypertrophic progression and extracellular signalling

    Författare :Nina Gennebäck; Stellan Mörner; Anders Waldenström; Urban Hellman; Ali J Marian; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac hypertrophy; HCM; gene expression; OPLS-DA; multivariate dataanalysis; cardiomyocytes; exosomes; microvesicles; Medicine; medicin;

    Sammanfattning : Background: The aim of this thesis was to study transcription patterns and extracellular signalling of the hypertrophic heart to better understand the mechanisms initiating, controlling and maintaining cardiac hypertrophy.Cardiac hypertrophy is a risk factor for cardiovascular morbidity and mortality. LÄS MER