Avancerad sökning
Visar resultat 1 - 5 av 25 avhandlingar som matchar ovanstående sökkriterier.
1. Genetics of complex disease
Sammanfattning : To find true genetic associations in complex diseases, such as allergic rhinitis and chronic rhinosinusitis, is a difficult task. Both are polygenetic diseases where it is believed that genetic variation in several genes make up their phenotypes. LÄS MER
2. The effect of common and rare variants on inflammatory traits and diseases
Sammanfattning : Genome wide association studies (GWAS) have identified thousands of loci associated to an immense number of traits and diseases. Most associations have been to common variants, but rare variant associations are progressively being reported. LÄS MER
3. Using systems genetics to explore the complexity of leaf shape variation in Populus tremula
Sammanfattning : Leaves are essential for sustaining humanity as they function as the energy and oxygen-producing organ of plants. Intensive research on physiological processes has contributed immensely to our understanding of the function of leaves. However, comparatively little is known about how leaf size and shape is determined. LÄS MER
4. Novel statistical methods for genome-wide association summary statistics
Sammanfattning : A general objective of genetic studies is to understand the genetic basis of complex traits such as height, body mass index (BMI), disease endpoints, etc. Such researches have been facilitated due to the completion of the human genome project and developments of high-throughput technologies. LÄS MER
5. Genetic factors affecting pregnancy duration in humans
Sammanfattning : This thesis investigates the mechanisms behind human pregnancy duration. Too short gestation is a direct cause of perinatal, neonatal, and infant mortality. Deviation from normal pregnancy length is also associated with a child's morbidity, even in the adulthood. LÄS MER