Sökning: "Genetic influences"

Visar resultat 1 - 5 av 186 avhandlingar innehållade orden Genetic influences.

1. 1. Alcohol Consumption among Adolescents : Psychosocial and Genetic influences

   Författare :Erika Comasco; Kent W. Nilsson; Lars Oreland; Rainer Spanagel; Uppsala universitet; []
   Nyckelord :adolescents; alcohol; biomarkers; depression; drinking motives; FAEE; gene environment interaction; interview; OPRM1; PER2; PEth; questionnaire; sleep; Neuroscience; Neurovetenskap;

   Sammanfattning : The present thesis is based on four studies focusing on alcohol consumption among Swedish adolescents, and therewith related psychosocial and genetic factors. One main objective was to study the reasons for drinking alcohol among different population - representative samples of adolescents in order to identify motives for drinking. LÄS MER

3. 2. Involvement of the Opioid System in High Alcohol Consumption : Environmental and Genetic Influences

   Författare :Karolina Ploj; Jörgen A Engel; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Opioids; ethanol; stress; maternal separation; neonatal handling; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

   Sammanfattning : It is well accepted that both inherent and environmental factors influence the pathogenesis of alcohol dependence. This thesis investigates the role of the opioid system in the initiation and maintenance of high ethanol intake. LÄS MER

4. 3. Advances in studying the role of genetic divergence and recombination in adaptation in non-model species

   Författare :Ramprasad Neethiraj; Christopher Wheat; Sören Nylin; Mathieu Joron; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Recombination; Genetic divergence; Lepidoptera; Genetic variation; Genetic diversity; Holocentric chromosomes; cis-regulatory variation; Allele-specific expression; populationsgenetik; Population Genetics;

   Sammanfattning : Understanding the role of genetic divergence and recombination in adaptation is crucial to understanding the evolutionary potential of species since they can directly affect the levels of genetic variation present within populations or species. Genetic variation in the functional parts of the genome such as exons or regulatory regions is the raw material for evolution, because natural selection can only operate on phenotypic variation already present in the population. LÄS MER

5. 4. Genetic and non-genetic influences on some metabolic cardiovascular risk factors : quantitative genetic analyses

   Författare :Yuling Hong; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cardiovascular risk factors; heritability; twins; adoption; insulin resistance syndrome; IGF-I; IGFBP-I; PAI-l; blood pressure; triglycerides; Lp a ; obesity.;

   Sammanfattning : Structural-equation modeling analyses were applied to data from 302 Swedish twin pairs in order to assess the relative importance of genetic and nongenetic influences on several metabolic cardiovascular risk factors. These middle-aged and elderly twins include monozygotic and dizygotic twins reared apart and together, who came from a population-based national twin register. LÄS MER

7. 5. Ecological drivers and genetic signatures of evolutionary divergence and local adaptation in pike (Esox lucius)

   Författare :Johanna Sunde; Anders Forsman; Anssi Laurila; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; adaptation; differentiation; Esox lucius; evolution; gene flow; genetic admixture; genetic structure; microsatellites; pike; RADseq; salinity tolerance; temperature tolerance; Ecology; Ekologi;

   Sammanfattning : The diversity among species, populations, and individuals in nature is astonishing. Genetic and phenotypic variation constitutes the raw material for evolution. It influences how populations respond to changing environments, and can impact long-term survival of species and ecosystem functioning. LÄS MER