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Visar resultat 1 - 5 av 51 avhandlingar som matchar ovanstående sökkriterier.
1. Cardiovascular response to hyperoxemia, hemodilution and burns : a clinical and experimental study
Sammanfattning : The last decades less invasive monitoring and analytical tools have been developed for the evaluation of myocardial mechanics in clinical praxis. In critical care, these are longed-for complements to pulmonary artery catheter monitoring, additionally offering previously inaccessible information. LÄS MER
2. Pharmacometric Models in Anesthesia and Analgesia
Sammanfattning : Modeling is a valuable tool in drug development, to support decision making, improving study design, and aid in regulatory approval and labeling. This thesis describes the development of pharmacometric models for drugs used in anesthesia and analgesia. LÄS MER
3. Aspects of neonatal intensive care and anesthesia : Thermal balance and respiratory management
Sammanfattning : This thesis is based on four articles originating from three studies conducted in the neonatal intensive care unit and the children’s operating deparment at Uppsala University Hospital, Sweden.The overall aim was to obtain new knowledge about thermal balance and care environment in extremely preterm infants during skin-to-skin care (SSC), evaluate different methods of intraoperative monitoring of carbon dioxide (CO2), and to investigate how different levels of inhaled oxygen affect infants’ oxygenation during anesthesia and surgery. LÄS MER
4. Nonlinear Modeling and Feedback Control of Drug Delivery in Anesthesia
Sammanfattning : General anesthesia is a drug-induced reversible state where neuromuscular blockade (NMB), hypnosis, and analgesia (jointly denoted by depth of anesthesia - DoA) are guaranteed. This thesis concerns mathematical modeling and feedback control of the effect of the muscle relaxants atracurium and rocuronium, the hypnotic propofol, and the analgesic remifentanil. LÄS MER
5. Maternal Hemodynamic Effects of Medical Gases and Uterotonics in Obstetrics
Sammanfattning : Aim of study: To elucidate the hemodynamic effects of pharmaceutical and medical interventions during pregnancy and childbirth on the mother.Introduction: Oxytocin, oxygen, and nitrous oxide are pharmaceuticals very commonly used in labor and delivery. These pharmaceuticals have known cardiovascular adverse effects. LÄS MER