Sökning: "Gene x environment interaction"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Gene x environment interaction.

1. 1. Depression and Antisocial Behaviour in Adolescents : Influence of Social Status, Shaming, and Gene-Environment Interaction

   Författare :Cecilia Åslund; Kent W Nilsson; Jerzy Leppert; Bengt Starrin; Lars Oreland; Lil Träskman-Bendz; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescent; antisocial behaviour; depression; gene-environment interaction; maltreatment; monoamine oxidase; serotonin; shame; social status; Child and adolescent psychiatry; Barn- och ungdomspsykiatri; barn- och ungdomspsykiatri; Child and Youth Psychiatry;

   Sammanfattning : This thesis investigated (1) social status and shaming experiences in relation to aggressive behaviour and depression, and (2) gene-environment interactions between two genetic polymorphisms related to the serotonergic system – MAOA-VNTR and 5HTTLPR – and experiences of maltreatment in relation to delinquent behaviour and depression among adolescents. The four included studies are based on questionnaire data from the Survey of Adolescent Life in Vestmanland 2006 (SALVe-2006). LÄS MER

3. 2. Gene x lifestyle interactions in type 2 diabetes mellitus and related traits

   Författare :Ema C Brito; Paul Franks; Aline Meirhaeghe; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gene x environment interaction; gene x lifestyle interaction; physical activity; type 2 diabetes; European Youth Heart Study; Malmö Preventive Project; Prevalence and Prediction and Prevention of Diabetes in Botnia; PPARGC1A; CDKN2A B; HNF1B; TCF7L2; FTO; Epidemiology; Epidemiologi; epidemiologi; Epidemiology; genetik; Genetics;

   Sammanfattning :   Background: Type 2 diabetes is thought to result from interactions between genetic and lifestyle factors, but few robust examples exist. The overarching aim of this thesis was to discover such interactions by studying cohorts of white youth and adults from northern Europe in which physical activity, genotypes, and diabetes-related traits or diabetes incidence had been ascertained. LÄS MER

4. 3. The effect of enriched environment on gene expression and stroke recovery

   Författare :Annica Rönnbäck; Tommy Olsson; Peter Eriksson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; experimental stroke; recovery; memory; inducible transcription factors; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Sammanfattning : Stroke is the third leading cause of death and the major course of long-term disabilities in industrialized countries. Most surviving stroke patients show some degree of spontaneous recovery, but persistent symptoms in sensorimotor and cognitive functions are common. LÄS MER

5. 4. Alcohol Consumption among Adolescents : Psychosocial and Genetic influences

   Författare :Erika Comasco; Kent W. Nilsson; Lars Oreland; Rainer Spanagel; Uppsala universitet; []
   Nyckelord :adolescents; alcohol; biomarkers; depression; drinking motives; FAEE; gene environment interaction; interview; OPRM1; PER2; PEth; questionnaire; sleep; Neuroscience; Neurovetenskap;

   Sammanfattning : The present thesis is based on four studies focusing on alcohol consumption among Swedish adolescents, and therewith related psychosocial and genetic factors. One main objective was to study the reasons for drinking alcohol among different population - representative samples of adolescents in order to identify motives for drinking. LÄS MER

7. 5. Interaction and regulation of asthma susceptibility genes

   Författare :Christina Orsmark Pietras; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Asthma is a disorder characterized by symptoms such as wheezing, shortness of breath, chest tightness or coughing. It is a chronic inflammation in the airways and the inflammation is usually accompanied by limitations in airflow as a result of hyper-secretion of mucus and broncho-constriction. LÄS MER